Z Geburtshilfe Neonatol 2024; 228(05): 458-460
DOI: 10.1055/a-2279-6803
Case Report

Enterovirus Infection in Preterm Quadruplets with Clinical Presentation of Neonatal Late-Onset Sepsis: a Case Report

Viktor Seifert
1   University Children's Hospital, Würzburg, Germany
,
Lena Böck
1   University Children's Hospital, Würzburg, Germany
,
Johannes Wirbelauer
1   University Children's Hospital, Würzburg, Germany
› Author Affiliations

Abstract

This is the unusual case of concurrent late-onset sepsis caused by enteroviruses in preterm quadruplets in a neonatal ward. While viral infections are an important differential diagnosis of bacterial sepsis in the outpatient setting, the occurrence in a neonatal ward with strict prophylactic hygiene measures is unusual. In this case, transmission of enteroviruses via breast milk appears possible.



Publication History

Received: 18 November 2023

Accepted after revision: 18 February 2024

Article published online:
15 April 2024

© 2024. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 
  • References

  • 1 Civardi E, Tzialla C, Baldanti F. et al. Viral outbreaks in neonatal intensive care units: what we do not know. Am J Infect Control 2013; 41: 854-856
  • 2 Hassan M, Khalil A, Magboul S. et al. Neonates and young infants with COVID-19 presented with sepsis-like syndrome: a retrospective case controlled study. Front Pediatr 2021; 9: 634844
  • 3 de Jong EP, van den Beuken MGA, van Elzakker EPM. et al. Epidemiology of sepsis-like illness in young infants: major role of enterovirus and human parechovirus. Pediatr Infect Dis J 2018; 37: 113-118
  • 4 Kidszun A, Klein L, Winter J. et al. Viral infections in neonates with suspected late-onset bacterial sepsis-a prospective cohort study. Am J Perinatol 2017; 34: 1-7
  • 5 Verboon-Maciolek MA, Thijsen SFT, Hemels MAC. et al. Inflammatory mediators for the diagnosis and treatment of sepsis in early infancy. Pediatr Res 2006; 59: 457-461
  • 6 Maus MV, Posencheg MA, Geddes K. et al. Detection of echovirus 18 in human breast milk. J Clin Microbiol 2008; 46: 1137-1140