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DOI: 10.1055/a-2217-2869
Einfluss von andauerndem Schmerz und Medikamenten auf das Sturz- und Frakturrisiko
Influence of Persistent Pain and Drugs on Falls and Fracture RiskZusammenfassung
Die Prävalenz von Schmerzen steigt mit dem Alter, ebenso wie die Anzahl der gleichzeitig vorliegenden Erkrankungen. Diese Multimorbidität triggert zudem die Verordnung zahlreicher Medikamente. Diese sog. Polypharmazie oder die Verordnung bestimmter Medikamentengruppen wie Analgetika, Hypnotika oder Antidepressiva sind mit der Häufigkeit von Sturzereignissen und Frakturen assoziiert. Diese Assoziation verleitet dazu, durch eine Reduktion der Anzahl der verordneten Medikamente ungünstige Ereignisse zu verhindern. Die Evidenz für diesen Ansatz konnte in randomisierten Studien jedoch nicht erbracht werden. Das Management der Medikation im Alter erfordert eine klare Indikation für ein Präparat, die regelmäßige Überprüfung dieser Indikation und die Auswahl des am besten verträglichen Präparates.
Abstract
The prevalence of pain increases with age, as does the number of co-existing diseases. This multimorbidity also triggers the prescription of numerous drugs. This so-called polypharmacy or the prescription of certain groups of drugs such as analgesics, hypnotics or antidepressants are associated with the frequency of falls and fractures. This association leads to the idea to prevent adverse events by reducing the number of drugs prescribed. However, the evidence for this approach could not be provided in randomized studies. Medication management in old age requires a clear indication for a drug, regular review of this indication, and selection of the most well-tolerated drug.
Schlüsselwörter
Andauernder Schmerz - Polypharmazie - Sturzereignisse - Frakturen - höheres LebensalterPublication History
Received: 11 September 2023
Accepted: 21 November 2023
Article published online:
20 February 2024
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