Intensivmedizin up2date 2024; 20(01): 105-122
DOI: 10.1055/a-2133-5178
Operative Intensivmedizin

Chirurgie im hohen Lebensalter

Mathilda Knoblauch
,
Thomas Saller
,
Bernhard W. Renz

Die Behandlungsbedürftigkeit älterer Patient*innen wird durch den demografischen Wandel kontinuierlich zunehmen. Operationsindikationen bei geriatrischen Patient*innen reichen von Eingriffen zur Verbesserung der Lebensqualität über die Behandlung maligner Erkrankungen bis zu Notfallsituationen wie einer Hohlorganperforation, traumatischen oder ischämischen Ereignissen oder einer Blutung.

Kernaussagen
  • Eine umfassende präoperative Evaluierung älterer Patient*innen ist notwendig, um mögliche Risiken zu identifizieren und eine individuell angepasste Behandlungsstrategie zu entwickeln.

  • Kalendarisches Alter per se ist kein Ausschlusskriterium in der Chirurgie.

  • Die allgemeine Gesundheit der Patient*innen, bestehende Co-Morbiditäten und kognitive Funktionen spielen eine wichtige Rolle bei der präoperativen Einschätzung der Patient*innen.

  • Bei guter präoperativer Selektion können auch größere Eingriffe mit guten Kurz- und Langzeitresultaten durchgeführt werden.

  • Durch minimalinvasive Operationsverfahren und Regionalverfahren der Anästhesie profitieren auch Risikopatienten von Operationen.

  • Postoperativ ist eine Optimierung der Schmerztherapie und frühe Mobilisation unabdingbar.

  • Eine individualisierte Herangehensweise und ein ganzheitlicher Blick auf die Patient*innen sind notwendig, um optimale Ergebnisse und eine verbesserte postoperative Genesung zu erzielen.



Publication History

Article published online:
22 March 2024

© 2024. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 
  • Literatur

  • 1 Hamel MB, Henderson WG, Khuri SF. et al. Surgical outcomes for patients aged 80 and older: morbidity and mortality from major noncardiac surgery. J Am Geriatr Soc 2005; 53: 424-429
  • 2 Peri-interventional outcome study in the elderly in Europe: A 30-day prospective cohort study. Eur J Anaesthesiol [Anonym]. 2022; 39: 198-209
  • 3 Herminghaus A, Löser S, Wilhelm W. [Anesthesia for geriatric patients. Part 1: age, organ function and typical diseases]. Anaesthesist 2012; 61: 163-174
  • 4 Keefover RW. Aging and cognition. Neurol Clin 1998; 16: 635-648
  • 5 Rivera R, Antognini JF. Perioperative drug therapy in elderly patients. Anesthesiology 2009; 110: 1176-1181
  • 6 Argillander TE, Heil TC, Melis RJF. et al. Preoperative physical performance as predictor of postoperative outcomes in patients aged 65 and older scheduled for major abdominal cancer surgery: A systematic review. Eur J Surg Oncol 2022; 48: 570-581
  • 7 Sabaté S, Mases A, Guilera N. et al. Incidence and predictors of major perioperative adverse cardiac and cerebrovascular events in non-cardiac surgery. Br J Anaesth 2011; 107: 879-890
  • 8 Sioutas G, Tsoulfas G. Frailty assessment and postoperative outcomes among patients undergoing general surgery. Surgeon 2020; 18: e55-e66
  • 9 Birkelbach O, Mörgeli R, Spies C. et al. Routine frailty assessment predicts postoperative complications in elderly patients across surgical disciplines – a retrospective observational study. BMC Anesthesiol 2019; 19: 204
  • 10 Robinson TN, Wu DS, Pointer L. et al. Simple frailty score predicts postoperative complications across surgical specialties. Am J Surg 2013; 206: 544-550
  • 11 Partridge JS, Harari D, Dhesi JK. Frailty in the older surgical patient: a review. Age Ageing 2012; 41: 142-147
  • 12 Tagliafico AS, Bignotti B, Torri L. et al. Sarcopenia: how to measure, when and why. Radiol Med 2022; 127: 228-237
  • 13 Petermann-Rocha F, Balntzi V, Gray SR. et al. Global prevalence of sarcopenia and severe sarcopenia: a systematic review and meta-analysis. J Cachexia Sarcopenia Muscle 2022; 13: 86-99
  • 14 Cederholm T, Jensen GL, Correia M. et al. GLIM criteria for the diagnosis of malnutrition – A consensus report from the global clinical nutrition community. Clin Nutr 2019; 38: 1-9
  • 15 Schaupp A, Martini S, Schmidmaier R. et al. Diagnostisches und therapeutisches Vorgehen bei Sarkopenie. Z Gerontol Geriatr 2021; 54: 717-724
  • 16 Ferrari U, Drey M. Die aktuelle Sarkopenie-Definition. Dtsch Med Wochenschr 2020; 145: 1315-1319
  • 17 Drey M, Ferrari U, Schraml M. et al. German Version of SARC-F: Translation, Adaption, and Validation. J Am Med Dir Assoc 2020; 21: 747-751
  • 18 Khatib-Chahidi K, Troja A, Kramer M. et al. [Preoperative management for malnourished patients in abdominal surgery. Practical treatment regimen for reduction of perioperative morbidity]. Chirurg 2014; 85: 520-528
  • 19 Shi Y, Zhou L, Yan E. et al. Sarcopenia and perioperative management of elderly surgical patients. Front Biosci (Landmark Ed) 2021; 26: 882-894
  • 20 Ergenc M, Karpuz S, Ergenc M. et al. Enhanced recovery after pancreatic surgery: A prospective randomized controlled clinical trial. J Surg Oncol 2021; 124: 1070-1076
  • 21 Neuman MD, Feng R, Carson JL. et al. Spinal anesthesia or general anesthesia for hip surgery in older adults. N Engl J Med 2021; 385: 2025-2035
  • 22 O’Brien K, Feng R, Sieber F. et al. Outcomes with spinal versus general anesthesia for patients with and without preoperative cognitive impairment: Secondary analysis of a randomized clinical trial. Alzheimers Dement 2023; 19: 4008-4019
  • 23 Feldheiser A, Aziz O, Baldini G. et al. Enhanced Recovery After Surgery (ERAS) for gastrointestinal surgery, part 2: consensus statement for anaesthesia practice. Acta Anaesthesiol Scand 2016; 60: 289-334
  • 24 Chang CY, Wu MY, Chien YJ. et al. Anesthesia and Long-term Oncological Outcomes: A Systematic Review and Meta-analysis. Anesth Analg 2021; 132: 623-634
  • 25 Schäfer ST, Andres C. Update on fast-track concepts in operative medicine : Improved outcome and higher patient satisfaction through interdisciplinary multimodal treatment concepts. Anaesthesiologie 2023; 72: 81-88
  • 26 Marsman M, Kappen TH, Vernooij LM. et al. Association of a Liberal Fasting Policy of Clear Fluids Before Surgery With Fasting Duration and Patient Well-being and Safety. JAMA Surg 2023; 158: 254-263
  • 27 Payne T, Braithwaite H, McCulloch T. et al. Depth of anaesthesia and mortality after cardiac or noncardiac surgery: a systematic review and meta-analysis of randomised controlled trials. Br J Anaesth 2023; 130: e317-e329
  • 28 Morris FJD, Fung YL, Craswell A. et al. Outcomes following perioperative red blood cell transfusion in patients undergoing elective major abdominal surgery: a systematic review and meta-analysis. Br J Anaesth 2023; 131: 1002-1013
  • 29 Wang D, Dong T, Shao Y. et al. Laparoscopy versus open appendectomy for elderly patients, a meta-analysis and systematic review. BMC Surg 2019; 19: 54
  • 30 Seishima R, Okabayashi K, Hasegawa H. et al. Is laparoscopic colorectal surgery beneficial for elderly patients? A systematic review and meta-analysis. J Gastrointest Surg 2015; 19: 756-765
  • 31 Garbarino GM, Costa G, Frezza B. et al. Robotic versus open oncological gastric surgery in the elderly: a propensity score-matched analysis. J Robot Surg 2021; 15: 741-749
  • 32 Khadaroo RG, Warkentin LM, Wagg AS. et al. Clinical effectiveness of the elder-friendly approaches to the surgical environment initiative in emergency general surgery. JAMA Surg 2020; 155: e196021
  • 33 SEER Cancer Statistics Review, 1975–2018, based on November 2020 SEER data submission, posted to the SEER web site, April 2021. Howlader N, Noone AM, Krapcho M, Miller D, Brest A, Yu M, Ruhl J, Tatalovich Z, Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA. Bethesda, MD: 2021. Accessed February 06, 2024 at: https://seer.cancer.gov/csr/1975_2018/
  • 34 Renz BW, Khalil PN, Mikhailov M. et al. Pancreaticoduodenectomy for adenocarcinoma of the pancreatic head is justified in elderly patients: A Retrospective Cohort Study. Int J Surg 2016; 28: 118-125
  • 35 Li N, Liu Y, Chen H. et al. Efficacy and safety of enhanced recovery after surgery pathway in minimally invasive colorectal cancer surgery: a systemic review and meta-analysis. J Laparoendosc Adv Surg Tech A 2023; 33: 177-187
  • 36 Pfeufer D, Zeller A, Mehaffey S. et al. Weight-bearing restrictions reduce postoperative mobility in elderly hip fracture patients. Arch Orthop Trauma Surg 2019; 139: 1253-1259
  • 37 Rapp K, Becker C, Todd C. et al. The association between orthogeriatric co-management and mortality following hip fracture. Dtsch Arztebl Int 2020; 117: 53-59
  • 38 Rayner C, Adams H. Aortic stenosis and transcatheter aortic valve implantation in the elderly. Aust J Gen Pract 2023; 52: 458-463
  • 39 Boskovski MT, Gleason TG. Current therapeutic options in aortic stenosis. Circ Res 2021; 128: 1398-1417
  • 40 Biscaglia S, Guiducci V, Escaned J. et al. Complete or culprit-only pci in older patients with myocardial infarction. N Engl J Med 2023; 389: 889-898
  • 41 Prendes CF, Dayama A, Panneton JM. et al. Endovascular aortic repair in nonagenarian patients. J Am Coll Cardiol 2021; 77: 1891-1899
  • 42 Tang GHL, Tadros RO. Endovascular aortic repair in nonagenarians: select well and time appropriately. J Am Coll Cardiol 2021; 77: 1900-1902