Pharmacopsychiatry 2023; 56(04): 162-164
DOI: 10.1055/a-2108-2164
Original Paper

Revisiting the World’s Strictest COVID-19 Lockdown: Formidable Mental Health Challenges

Beier Guan*
1   Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China
,
Ruihua Li*
1   Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China
,
Chuanning Huang*
1   Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China
,
Jiang Du
1   Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China
,
Min Zhao
1   Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China
2   Shanghai Key Laboratory of Psychotic Disorders, Shanghai, China
3   CAS Center for Excellence in Brain Science and Intelligence Technology (CEBSIT), Chinese Academy of Sciences, Shanghai, China
,
Shuyan Liu
4   Department of Psychiatry and Psychotherapy, Charité – Universitätsmedizin Berlin (Campus Charité Mitte), Berlin, Germany
› Author Affiliations
Funding This research was funded by Shanghai Municipal Science and Technology Major Project (2018SHZDZX05), Shanghai Clinical Research Center for Mental Health (M.Z., 19MC1911100), and Shanghai Shenkang Hospital Development Center (M.Z., SHDC2020CR3045B); National Nature Science Foundation of China (8187051622, 8217050343 to J.D), Science and Technology Commission of Shanghai Municipal (21DZ2201000 to J.D).

Abstract

Introduction Many nations have implemented lockdowns to prevent and minimize the spread of infections in healthcare settings. However, the impact of lockdown duration on mental health remains controversial.

Methods We conducted a retrospective study using online questionnaires to assess the mental health status of the general population during the Shanghai lockdown period from March to May 2022. The mental health of the participants was evaluated by the 12-item General Health Questionnaire (GHQ-12), in which a cut-off score of 12 or more indicated psychological distress. A logistic regression model was used to evaluate the relationship between lockdown duration and mental health.

Results Among 2139 participants (mean age: 26.12 years, standard deviation: 6.37, 731 females; 1378 unmarried; 1099 Shanghai residents), approximately 47% reported psychological distress (GHQ-12≥12). Participants exposed to lockdown reported significantly higher GHQ-12 scores (11.93±6.81 vs. 8.73±6.35, p<0.001). In our logistic regression model, participants who experienced the longest lockdown (43–61 days) had a significantly higher risk of psychological distress compared with those who did not (odds ratio: 3.10, 95% confidence interval: 2.06–4.70, p<0.001).

Discussion Lockdown duration significantly affects mental health, with longer lockdown duration being associated with worse mental health status. The relationship between lockdown and mental health should not be neglected in case of lockdown in response to future pandemics.

* Equal contribution: Beier Guan, Ruihua Li, Chuanning Huang




Publication History

Received: 12 February 2023

Accepted: 25 May 2023

Article published online:
12 July 2023

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