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Zeitschrift für Orthomolekulare Medizin 2023; 21(01): 16-24
DOI: 10.1055/a-2014-4012
DOI: 10.1055/a-2014-4012
Wissen
Autoimmunerkrankungen und Vitamin D
![](https://www.thieme-connect.de/media/OM/202301/lookinside/thumbnails/20144012_10-1055-a-2014-4012-1.jpg)
Zusammenfassung
Die biologisch aktive Form von Vitamin D, das Secosteroidhormon 1,25(OH)2D, moduliert zahlreiche Gene des angeborenen und adaptiven Immunsystems über Regulation seines Transkriptionsfaktors Vitamin-D-Rezeptor (VDR). Der Beitrag stellt den Einfluss des Prohormons auf das Epigenom vor und den aktuellen Stellenwert in der Therapie von Autoimmunerkrankungen, z. B. Multiple Sklerose, sowie bei einer Vitamin-D-Resistenz.
Schlüsselwörter
Autoimmunerkrankungen - Vitamin D - Vitamin-D-Rezeptor - Multiple Sklerose - Parathormon - Epigenom - DNA-Methylierung - Vitamin-D-Resistenz - Coimbra-ProtokollPublication History
Article published online:
24 March 2023
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