Radiopraxis 2023; 16(04): 169-181
DOI: 10.1055/a-1830-5199
CPD-Fortbildung

Differenzierung struktureller Herzerkrankungen in der MRT

Differentiation of Structural Heart Disease on MRI
Barbara Hoche
,
Linus Schuck

Strukturelle Herzerkrankungen umfassen erworbene oder angeborene Veränderungen, die mit einer Modifizierung der Herzklappen und des Herzmuskels einhergehen. Eine Verdickung des Herzmuskels gibt indirekte Hinweise für eine vergrößerte interstitielle Matrix, d. h., dass sich im Extrazellulärraum pathologische Stoffwechselabbauprodukte angesammelt haben und diese funktionelle Defizite in der Kontraktion des Herzmuskels verursachen können.

Abstract

Structural heart disease includes changes, which may be acquired or congenital, in the heart valves and heart muscle. The boundaries between congenital and acquired diseases are blurred and cannot be clearly defined. Thickening of the myocardium is an indirect indication of an enlarged interstitial matrix, which means that pathological metabolic degradation products such as fatty deposits (Fabry disease), amyloid proteins (amyloidosis), granulocytes (sarcoidosis) or fibrosis (CMP cardiomyopathy) accumulate in the extracellular space and can lead to functional deficits in the contraction of the myocardium.



Publikationsverlauf

Artikel online veröffentlicht:
28. November 2023

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