Synlett 2022; 33(10): 983-987
DOI: 10.1055/a-1801-4344
letter

Synthesis of the Icetexane Diterpenoids (±)-Rosmaridiphenol, (±)-Pisiferin, and (±)-Barbatusol from Abietane

Thuy Quynh Le
,
JuHui Lee
,
Chang Ho Oh
This research was supported by a Basic Science Research Program through the National Research Foundation of Korea (NRF), funded by the Ministry of Education (NRF-2021R1F1A1049992).


Abstract

We report the rearrangement of abietane core with trifluoromethanesulfonic anhydride in pyridine to afford the icetexane core, a key intermediate for total syntheses of the structurally intriguing and biologically active compounds (±)-barbatusol, (±)-rosmaridiphenol, and (±)-pisiferin.

Supporting Information



Publication History

Received: 08 February 2022

Accepted after revision: 17 March 2022

Accepted Manuscript online:
17 March 2022

Article published online:
12 April 2022

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