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Zahnmedizin up2date 2021; 15(01): 67-75
DOI: 10.1055/a-1387-1171
Varia

Adipositas als Risikofaktor für Parodontitis

Henrike März
,
Bernd W. Sigusch
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Adipositas gilt als Risikofaktor für die Entstehung der Parodontitis. Dabei sind die zugrunde liegenden Mechanismen sehr vielfältig. Eine effektive Therapie berücksichtigt die verschiedenen Einflussfaktoren und setzt sowohl lokal am Infektions- und Entzündungsgeschehen in der Mundhöhle, aber auch systemisch am Ernährungs- und Lebensstil an. Um Patienten bei der Gewichtsreduktion unterstützen zu können, liefert dieser Fortbildungsbeitrag Informationen zur Charakterisierung und Behandlung von Übergewicht im Kontext der Parodontitis.

Publication History

Article published online:
15 March 2021

© 2021. Thieme. All rights reserved.

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  • Literatur

  • 1 Perlstein M, Bissada N. Influence of obesity and hypertension on the severity of periodontitis in rats. Oral Surg Oral Med Oral Pathol 1977; 43: 707-719
    CrossrefPubMedGoogle Scholar
  • 2 Al-Zahrani MS, Bissada NF, Borawski EA. Obesity and periodontal disease in young, middle-aged, and older adults. J Periodontol 2003; 74: 610-615
    CrossrefPubMedGoogle Scholar
  • 3 Vanhala M, Vanhala P, Kumpusalo E. et al. Relation between obesity from childhood to adulthoodand the metabolic syndrome: Population based study. BMJ 1998; 317: 319
    CrossrefPubMedGoogle Scholar
  • 4 Wood N, Johnson RB, Streckfus CF. Comparison of body composition and periodontal disease using nutritional assessment techniques: Third National Health and Nutrition Examination Survey (NHANES III). J Clin Periodontol 2003; 30: 321-327
    CrossrefPubMedGoogle Scholar
  • 5 Rexrode K, Carey V, Hennekens C. et al. Abdominal obesity and coronary heart disease in woman. JAMA 1998; 280: 1843-1848
    CrossrefPubMedGoogle Scholar
  • 6 Suvan J, Harrington Z, Petrie A. et al. Obesity as predictive factor of periodontal therapy clinical outcomes. A cohort study. J Clin Periodontol 2020; 47: 594-601
    CrossrefPubMedGoogle Scholar
  • 7 Pischon N, Heng N, Bernimoulin JP. et al. Obesity, inflammation, and periodontal disease. J Dent Res 2007; 86: 400-409
    CrossrefPubMedGoogle Scholar
  • 8 Genco RJ, Grossi SG. Ho Anet al. A proposed model linking inflammation to obesity, diabetes, and periodontal infections. J Periodontol 2005; 76: 2075-2084
    CrossrefPubMedGoogle Scholar
  • 9 Kim EJ, Jin BH, Bae KH. Periodontitis and obesity: a study of the Fourth Korean National Health an Nutrition Examination Survey. J Periodontol 2011; 82: 533-542
    CrossrefPubMedGoogle Scholar
  • 10 Gallagher D, Heymsfield SB, Heo M. et al. Healthy percentage body fat ranges: an approach for developing guidelines based on body mass index. Am J Clin Nutr 2000; 72: 694-701
    CrossrefPubMedGoogle Scholar
  • 11 Flegal KM. Excess deaths associated with underweight, overweight, and obesity. JAMA 2005; 293: 1861-1867
    CrossrefPubMedGoogle Scholar
  • 12 Ahima RS, Osei SY. Adipokines in obesity. Front Horm Res 2008; 36: 182-197
    CrossrefPubMedGoogle Scholar
  • 13 Eivazi M, Falahi N, Eivazi N. et al. The effect of scaling and root planning on salivary TNF-α and IL-1α concentrations in patients with chronic periodontitis. Open Dent J 2017; 11: 573-580
    CrossrefPubMedGoogle Scholar
  • 14 Alipourfad I, Datukishvili N, Mikeladze D. TNF-α downregulation modifies insulin receptor substrate-1 (IRS-1) in metabolic signaling of diabetic insulin-resistant hepatocytes. Mediators Inflamm 2019; 2019: 3560819
    PubMedGoogle Scholar
  • 15 Azuma Y, Kaji K, Katogi R. et al. Tumor necrosis factor-α induces differentiation of and bone resorption by osteoclasts. J Biol Chem 2000; 275: 4858-4864
    CrossrefPubMedGoogle Scholar
  • 16 Nigro E, Scudiero O, Monaco ML. et al. New insight into adiponectin role in obesity and obesity-related disease. Biomed Res Int 2014; 2014: 658913
    CrossrefPubMedGoogle Scholar
  • 17 Esfahani M, Movahedian A, Baranchi M. et al. Adiponectin: an adipokine with protective features against metabolic syndrome. Iran J Basic Med Sci 2015; 18: 430-442
    PubMedGoogle Scholar
  • 18 Higdon JV, Frei B. Obesity and oxidative stress – a direct link to CVD?. Arterioscler Thromb Vasc Biol 2003; 23: 365-367
    CrossrefPubMedGoogle Scholar
  • 19 Bournat JC, Brown CW. Mitochondrial dysfunction in obesity. Curr Opin Endocrinol Diabetes Obes 2010; 17: 446-452
    CrossrefPubMedGoogle Scholar
  • 20 Furukawa S, Fujita T, Shimabukuru M. et al. Increased oxidative stress in obesity and its impact on metabolic syndrome. J Clin Invest 2004; 114: 1752-1761
    CrossrefPubMedGoogle Scholar
  • 21 Sorochynska OM, Bayliak MM, Gospodaryov DV. et al. Every-other-day feeding decreases glycolytic and mitochondrial energy-producing potentials in the brain and liver of young mice. Front Physiol 2019; 10: 1432
    CrossrefPubMedGoogle Scholar
  • 22 La Fleur SE, Luijendijk MC, van der Zwaal EM. et al. The snacking rat as model of human obesity: effects of a free-choice high-fat high-sugar diet on meal patterns. Int J Obes 2014; 38: 643-649
    CrossrefPubMedGoogle Scholar
  • 23 Saito T, Shimazaki Y, Koga T. et al. Relationship between upper body obesity and periodontitis. J Dent Res 2001; 80: 1631-1636
    CrossrefPubMedGoogle Scholar
  • 24 Bianchi VE. Weight loss is a critical factor to reduce inflammation. Clin Nutr ESPEN 2018; 28: 21-35
    CrossrefPubMedGoogle Scholar
  • 25 Vivekananda L, Faizuddin M. Effect of weight reduction on the serum adiponectin and tumor necrosis factor-α levels and the clinical parameters of obese patients with and without periodontal disease. J Int Soc Prev Community Dent 2019; 9: 166-171
    CrossrefPubMedGoogle Scholar
  • 26 Dodington DW, Fritz PC, Sullivan PJ. et al. Higher intakes of fruits and vegetables, β-carotene, vitamin C, α-tocopherol, EPA and DHA are positively associated with periodontal healing after nonsurgical periodontal therapy in nonsmokers but not in smokers. J Nutr 2015; 145: 2512-2519
    CrossrefPubMedGoogle Scholar
  • 27 Carr AC, Maggini S. Vitamin C and immune function. Nutrients 2017; 9: 1211
    CrossrefPubMedGoogle Scholar
  • 28 Staudte H, Kranz S, Völpel A. et al. Comparison of nutrient intake between patients with periodontitis and healthy subjects. Quintessence Int 2012; 43: 907-916
    PubMedGoogle Scholar
  • 29 Merchant AT. Plasma vitamin C is inversely associated with periodontitis. J Evid Based Dent Pract 2008; 8: 103
    CrossrefPubMedGoogle Scholar
  • 30 Chung OK, Chung SJ, Claykombe KJ. et al. Serum C-reactive protein concentrations are inversely associated with dietary with dietary flavonoid intake in U.S. adults. J Nutr 2008; 138: 753-760
    CrossrefPubMedGoogle Scholar
  • 31 Dickinson S, Hancock DP, Petocz P. et al. High-glykemic index carbohydrate increases nuclear factor-kB activation in mononuclear cells of young lean healthy subjects. Am J Clin Nutr 2008; 87: 1188-1193
    PubMedGoogle Scholar
  • 32 Qi L, Hu FB. Dietary glycemic load, whole grains, and systemic inflammation in diabetes: the epidemiological evidence. Curr Opin Lipidol 2007; 18: 3-8
    CrossrefPubMedGoogle Scholar
  • 33 King DE, Egan BM, Woolson RF. et al. Effect of a high-fiber diet vs. a fiber-supplemented diet on C-reactive protein level. Arch Intern Med 2007; 167: 502-506
    CrossrefPubMedGoogle Scholar
  • 34 Freire MO, Van Dyke TE. Natural resolution of inflammation. Periodontol 2000 2013; 63: 149-164
    CrossrefPubMedGoogle Scholar
  • 35 Naqvi AZ, Buettner C, Phillips RS. et al. N-3 fatty acids and periodontitis in US adults. J Am Diet Assoc 2010; 110: 1669-1675
    CrossrefPubMedGoogle Scholar
  • 36 Ferreira RO, Correa MG, Magno MB. et al. Physical activity reduces the prevalence of periodontal disease: systematic review and meta-analysis. Front Physiol 2019; 10: 234
    CrossrefPubMedGoogle Scholar