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DOI: 10.1055/a-1336-6251
Klinische Studie zur Akutwirkung eines Phytopharmakons mit D-Campher und Crataegus auf Blutdruck und kognitive Funktionen
Clinical Study of the Effectivity of a Phytopharmaceutical Containing D-Camphor and Crataegus on Blood Pressure and Cognitive Functions![](https://www.thieme-connect.de/media/phyto/202302/lookinside/thumbnails/13366251_10-1055-a-1336-6251-1.jpg)
Zusammenfassung
In einer randomisierten doppelblinden placebokontrollierten klinischen Studie wurde untersucht, ob bei einer mäßigen Hypotonie eine medikamentöse Erhöhung des Blutdrucks mit einer Steigerung der kognitiven Leistung einhergeht. 120 Erwachsene mit einem systolischen Blutdruck von unter 119 mmHg (Männer) bzw. unter 111 mmHg (Frauen) nahmen teil. Sie erhielten entweder eine Campher-Weißdorn-Kombination als Verum (N=60) oder ein Placebo (N=60). Im Vergleich zur Placebogruppe kam es in der Verumgruppe zu einem signifikant höheren Anstieg des systolischen und mittleren arteriellen Blutdrucks sowie zu einer signifikant besseren Konzentrationsleistung und einer nahezu signifikant besseren selektiven Aufmerksamkeit. Die gute Verträglichkeit und die hohe Sicherheit des Phytopharmakons wurden konstatiert.
Abstract
A randomized, placebo-controlled clinical trial was conducted to determine whether a drug-induced increase in blood pressure is associated with an increase in cognitive performance in moderate hypotension. 120 adults with a systolic blood pressure below 119 mmHg (men) or below 111 mmHg (women) participated. They received either a camphor-hawthorn combination as verum (N=60) or a placebo (N=60). Compared to the placebo group, the verum group experienced significantly higher increases in systolic and mean arterial blood pressure, as well as a significantly better concentration performance and an almost significantly better selective attention. The good tolerability and safety of the phytopharmaceutical were confirmed.
Schlüsselwörter
Klinische RCT-Studie - Hypotonie - Kognition - Campher-Weißdorn-Phytopharmakon - SicherheitKey words
Clinical RCT study - camphor hawthorn phytopharmaceutical - hypotension - cognition - safetyPublication History
Article published online:
16 March 2023
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