Aktuelle Bewertung von Homocystein als Risikofaktor für Demenz

Zusammenfassung

Mit zunehmendem Lebensalter steigen die Homocysteinwerte im Blutplasma, unter anderem bedingt durch einen Mangel an B-Vitaminen wie Folat und den Vitaminen B₆ und B₁₂. In jüngeren Studien erwies sich die Hyperhomocystämie als ein modifizierbarer Risikofaktor für Demenz. Eine Senkung des Plasma-Homocysteins bei Patienten mit leichter kognitiver Dysfunktion und mehr als 14µmol / l Gesamthomocystein könnte eventuell den kognitiven Leistungsabbau bremsen.

Schlüsselwörter

Homocystein - Demenz - Vitamin B - Folat

• Literatur

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