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DOI: 10.1055/s-2008-1039191
© Georg Thieme Verlag KG Stuttgart · New York
Massive Bilateral Nephromegaly in Acute Lymphoblastic Leukemia: A Case Report
Publication History
Publication Date:
17 February 2009 (online)
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Introduction
Acute leukemia is the most common childhood malignancy, accounting for about one-third of all pediatric cancers. Acute lymphoblastic leukemia (ALL) constitutes about 75 % of childhood leukemias [11]. The disease involves the bone marrow and blood but occasionally presents with nodal or extranodal sites including renal involvement.
The most common sites of extramedullary involvement in ALL are the liver, spleen or lymph nodes; however, as many as 30 % of patients presenting with ALL in one study had renal involvement and about 10 % presented with bilateral nephromegaly. We report a rare case of a 15-month-old child with massive bilateral nephromegaly and pre-B cell ALL.
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Dr. M.D. Pablo Aguayo
Department of Surgery
Children's Mercy Hospital
2401 Gillham Road
Kansas City, MO 64108
USA
Email: paguayo@cmh.edu