Reevaluation of Patients with Clinically Probable Parkinson's Disease but Normal DAT Scan

In recent years about 200 patients with clinical probable Parkinson's disease treated at our outpatient unit were examined with DAT scan. As reported by other authors, about 10% of these examinations showed not a Parkinsonian, but a normal pattern. We clinically reevaluated 15 patients out of this subgroup about two years after the first examination. Our task was to find out what kind of disease developed out of the syndrome primarily estimated as Parkinson's disease. We performed a complete neurological examination, UPDRS together with video recording and evaluation by an independent neurologist, L-Dopa test, Hoehn and Yahr Scale, Schwab and England activities of daily living-scale, Montgomery-Asperg Demention Scale, PDQ39 and Nürnberger Self Evaluation Scale. We hope to be able to provide an aid for the evaluation of patients with clinically probable Parkinson's disease who do not profit by dopaminergic treatment and show a normal pattern in the DAT scan.