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DOI: 10.1055/s-2004-822706
© Georg Thieme Verlag Stuttgart · New York
Kolorektales Karzinom - Rationelle Diagnostik und klinisches Staging
Colorectal Cancer - Rational Diagnostics and Clinical StagingPublication History
Publication Date:
06 July 2004 (online)
Zusammenfassung
Zur Abklärung eines Verdachts auf das Vorliegen eines kolorektalen Karzinoms ist die Durchführung einer kompletten Koloskopie obligat. Nach Karzinomdiagnose sollten im Rahmen des präoperativen Stagings routinemäßig eine Abdomen-Sonographie, ein Röntgen-Thorax sowie eine CEA-Bestimmung erfolgen. Der Familienanamnese kommt eine wichtige Bedeutung zu, um hereditäre Darmkrebsformen zu identifizieren. Beim Rektumkarzinom ist eine weitere lokale Bildgebung zur operativen Planung und Beurteilung der Notwendigkeit einer neoadjuvanten Therapie wünschenswert. Beim Kolonkarzinom ist eine weitere bildgebende Diagnostik nur bei speziellen Fragestellungen wie dem Verdacht auf das Vorliegen von Metastasen erforderlich.
Abstract
Whenever a colorectal cancer is suspected a complete colonoscopy is required as the appropriate work up. Once the colorectal cancer diagnosis has been established the preoperative staging should include an abdominal ultrasound, a chest X-ray and a serum-CEA measurement. In order to identify hereditary colorectal cancer forms a thorough family history is mandatory. For the work up of a rectal cancer further local imaging is helpful for the surgical planning and to determine whether neoadjuvant therapy is warranted. The work up of a colon cancer only requires additional radiological imaging in special situations, e. g. if metastases are suspected.
Schlüsselwörter
Kolorektales Karzinom - Staging - präoperative Diagnostik
Key words
Colorectal cancer - preoperative staging - radiological imaging
Literatur
- 1 Rex D K, Rahmani E Y, Haseman J H. et al . Relative sensitivity of colonoscopy and barium enema for detection of colorectal cancer in clinical practice. Gastroenterology. 1997; 112 17-23
- 2 Barillari P, Ramacciato G, De Angelis R. et al . Effect of preoperative colonoscopy on the incidence of synchronous and metachronous neoplasms. Acta Chir Scand. 1990; 156 163-166
- 3 Neri E, Giusti P, Battolla L. et al . Colorectal cancer: role of CT colonography in preoperative evaluation after incomplete colonoscopy. Radiology. 2002; 223 615-619
- 4 Barton J B, Langdale L A, Cummins J S. et al . The utility of routine preoperative computed tomography scanning in the management of veterans with colon cancer. Am J Surg. 2002; 183 499-503
- 5 McAndrew M R, Saba A K. Efficacy of routine preoperative computed tomography scans in colon cancer. Am Surg. 1999; 65 205-208
- 6 Duffy M J, van Dalen A, Haglund C. et al . Clinical utility of biochemical markers in colorectal cancer: European Group on Tumour Markers (EGTM) guidelines. Eur J Cancer. 2003; 39 718-727
- 7 Church J M, Gibbs P, Chao M W, Tjandra J J. Optimizing the outcome for patients with rectal cancer. Dis Colon Rectum. 2003; 46 389-402
- 8 Matsuoka H, Nakamura A, Masaki T. et al . A prospective comparison between multidetector-row computed tomography and magnetic resonance imaging in the preoperative evaluation of rectal carcinoma. Am J Surg. 2003; 185 556-559
- 9 Mathur P, Smith J J, Ramsey C. et al . Comparison of CT and MRI in the pre-operative staging of rectal adenocarcinoma and prediction of circumferential resection margin involvement by MRI. Colorectal Dis. 2003; 5 396-401
- 10 Orrom W J, Wong W D, Rothenberger D A, Jensen L L, Goldberg S M. Endorectal ultrasound in the preoperative staging of rectal tumors. A learning experience. Dis Colon Rectum. 1990; 33 654-659
- 11 Marusch F, Koch A, Schmidt U. et al . Routine use of transrectal ultrasound in rectal carcinoma: results of a prospective multicenter study. Endoscopy. 2002; 34 385-390
- 12 Vasen H F, Watson P, Mecklin J P, Lynch H T. New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative group on HNPCC. Gastroenterology. 1999; 116 1453-1456
Dr. Christian Pox
Ruhr-Universität · Medizinische Klinik · Knappschaftskrankenhaus
In der Schornau 23-25
44892 Bochum
Phone: 02 34/2 99 34 01
Fax: 02 34/2 99 34 09
Email: christian.p.pox@ruhr-uni-bochum.de