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Seminars in Neurosurgery 2002; 13(2): 119-130
DOI: 10.1055/s-2002-35809
Copyright © 2002 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Chiari I Malformations and Syringomyelia

Ramin J. Javahery, Steven Vanni, Allan D.O. Levi
  • Department of Neurological Surgery, University of Miami School of Medicine, Lois Pope LIFE Center, Miami, Florida
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Publication History

Publication Date:
28 November 2002 (online)

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ABSTRACT

The pathogenesis of the Chiari I malformation (CMI) as well as its associated syringomyelic cavity remains relatively vague despite significant recent advances. Multiple theories have been proposed to explain both the origin of the CMI and the development of a syrinx. This article fleshes out the major theories for both of these conditions. The indeterminate quality of this condition can also be seen in its presentation. There are myriad documented presenting signs and symptoms in patients with CMI. The major clinical syndromes and most common signs and symptoms are reviewed. Most importantly for both patient and physician, this lack of consensus extends to treatment. Because of historical unsatisfying surgical results, a multitude of treatment options have been and are currently being proposed for the treatment of both conditions. The major schools of thought with regard to treatment are also reviewed.

KEYWORDS

Chiari malformation - syringomyelia - syrinx

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