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Seminars in Neurosurgery 2002; 13(1): 029-038
DOI: 10.1055/s-2002-35245
Copyright © 2002 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

The ABCs of Pediatric Head Trauma

Catherine A. Mazzola, P. David Adelson
  • Department of Neurosurgery, University of Pittsburgh, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania
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Publikationsverlauf

Publikationsdatum:
04. November 2002 (online)

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ABSTRACT

Traumatic injury is the leading cause of morbidity and mortality in children, and causes over half of all childhood deaths.[1] [2] [3] [4] Mortality rates of 30 to 50% have been reported for children with traumatic brain injury (TBI). Although children have better survival rates than adults, the long-term sequelae are more devastating in children due to their age and extended life expectancy.[5] Costs involved in care of a child with head injury, extended over the lifetime of the patient, are tremendous. It is unfortunate that despite preventive measures, TBI remains the major morbidity and mortality factor for children.

KEYWORDS

Brain injury - diffuse axonal injury - intracranial pressure - pediatric - shaken baby - trauma

REFERENCES

  • 1 Aldrich E F, Eisenberg H M, Saydjari C. Diffuse brain swelling in severely head injured children: a report from the NIH Traumatic Coma Data Bank.  J Neurosurg . 1992;  76 450-454
    CrossrefPubMedGoogle Scholar
  • 2 Hoyert D L, Freedman M A, Strobino D M, Guyer B. Annual summary of vital statistics.  Pediatrics . 2001;  108 1241-1255
    CrossrefPubMedGoogle Scholar
  • 3 Luerssen T G, Klauber M R, Marshall L F. Outcome from head injury related to patient's age.  J Neurosurg . 1988;  68 409-416
    CrossrefPubMedGoogle Scholar
  • 4 Wegman W E. Annual summary of vital statistics-1981.  Pediatrics . 1981;  75 835-843
    PubMedGoogle Scholar
  • 5 Shewmon D A. Coma prognosis in children.  J Clin Neurophys . 2000;  17 467-472
    PubMedGoogle Scholar
  • 6 Childhood injuries in the United States. Division of Injury Control, Center for Environmental Health and Injury Control, Centers for Disease Control.  Am J Dis Child . 1990;  144 627-647
    PubMedGoogle Scholar
  • 7 Kraus J F, Rock A, Hemyari P. Brain injuries among infants.  Am J Dis Child . 1990;  144 684-691
    PubMedGoogle Scholar
  • 8 Rivara F P. Childhood injuries.  Dev Med Child Neurol . 1984;  26 81-87
    PubMedGoogle Scholar
  • 9 Greenes D S, Schutzman S A. Clinical indicators of intracranial injury in head injured infants.  Pediatrics . 1999;  104 861-867
    CrossrefPubMedGoogle Scholar
  • 10 Quayle K S, Jaffe D M, Kuppermann N. Diagnostic testing for acute head injury in children.  Pediatrics . 1997;  99 E11
    PubMedGoogle Scholar
  • 11 Levin H S, Aldrich E F, Saydjari C. Severe head injury in children.  Neurosurgery . 1992;  31 435-444
    PubMedGoogle Scholar
  • 12 Forbes M T, Hendrich K S, Schiding J K. Perfusion-weighted MRI assessment of cerebral blood flow and CO2 reactivity after controlled cortical impact in rats (abstract).  J Neurotrauma . 1995;  12 988
    PubMedGoogle Scholar
  • 13 Orliaguet G, Lejay M. Pediatric trauma patients.  Current Opinion in Critical Care . 1999;  5 506-510
    PubMedGoogle Scholar
  • 14 Graham D I, Ford I, Adams J H. Fatal head injury in children.  J Clin Pathol . 1988;  42 18-22
    PubMedGoogle Scholar
  • 15 Graham D I, Lawrence A E, Adams J H. Brain damage in fatal nonmissile head injury without high intracranial pressure.  J Clin Pathol . 1988;  41 34-37
    PubMedGoogle Scholar
  • 16 Adelson P D, Clyde B, Kochanek P M. Cerebrovascular response in infants and young children following severe traumatic brain injury.  Pediatr Neurosurg . 1997;  26 200-207
    PubMedGoogle Scholar
  • 17 Ruppel R A, Kochanek P M, Adelson P D. Excitatory amino acid concentrations in ventricular cerebrospinal fluid after severe traumatic brain injury in infants and children.  J of Pediatrics . 2001;  138 18-25
    PubMedGoogle Scholar
  • 18 Choi D W, Maulucci-Gedde M, Kriegstein A R. Glutamate neurotoxicity in cortical cell culture.  J Neurosci . 1987;  7 357-368
    PubMedGoogle Scholar
  • 19 McDonald J W, Silverstein F S, Johnston M V. Neurotoxicity of N-methyl-D-aspartate is markedly enhanced in developing rat central nervous system.  Brain Res . 1988;  459 200-203
    CrossrefPubMedGoogle Scholar
  • 20 Fineman I, Hovda D A, Smith M. Concussive brain injury is associated with a prolonged accumulation of calcium: a 45Ca autoradiographic study.  Brain Res . 1993;  624 94-102
    CrossrefPubMedGoogle Scholar
  • 21 Bittigau P, Sifringer M, Pohl D. Apoptotic neurodegeneration following trauma is markedly enhanced in the immature brain.  Ann of Neurol . 1999;  45 724-735
    PubMedGoogle Scholar
  • 22 Schutzman S A, Greenes D S. Pediatric minor head trauma.  Annals of Emerg Med . 2001;  37 65-74
    PubMedGoogle Scholar
  • 23 Michaud L J, Rivara F P, Grady M S, Reay D T. Predictors of survival and severity of disability after severe head injury in children.  Neurosurgery . 1991;  31 254-264
    PubMedGoogle Scholar
  • 24 Levi L, Guilburd J N, Linn S. The association between skull fracture, intracranial pathology and outcome in pediatric head injury.  Br J Neurosurg . 1991;  5 617-625
    PubMedGoogle Scholar
  • 25 Keskil I S, Baykaner M K, Ceviker N. Assessment of mortality associated with mild head injury in the pediatric age group.  Childs Nerv Syst . 1995;  11 467-473
    CrossrefPubMedGoogle Scholar
  • 26 Wang M Y, Griffith P, Sterling J. A prospective population based study of pediatric trauma patients with mild alterations of consciousness (GCS 13-14).  Neurosurgery . 2000;  46 1093-1099
    PubMedGoogle Scholar
  • 27 Rosenthal B W, Bergman I. Intracranial injury after moderate head trauma in children.  J Pediatr . 1989;  115 346-350
    PubMedGoogle Scholar
  • 28 Schunk J E, Rodgerson J D, Woodward G A. The utility of head computed tomographic scanning in pediatric patients with normal neurologic examination in the emergency department.  Pediat Emerg Care . 1996;  12 160-165
    PubMedGoogle Scholar
  • 29 Simon B, Letourneau P, Vitorino E. Pediatric minor head trauma: indications for CT scanning revisited.  J Trauma . 2001;  51 231-238
    CrossrefPubMedGoogle Scholar
  • 30 Bergsneider M, Hovda D A, AcArthur D L. Metabolic recovery following human traumatic brain injury based on FDG-PET: time course and relationship to neurological disability.  J Head Trauma Rehabil . 2001;  16 135-148
    CrossrefPubMedGoogle Scholar
  • 31 Suh D Y, Davis P C, Hopkins K L. Nonaccidental pediatric head injury: diffusion weighted imaging findings.  Neurosurgery . 2001;  49 309-319
    CrossrefPubMedGoogle Scholar
  • 32 Brooks W M, Friedman S D, Gaspoarovic C. Magnetic resonance spectroscopy in traumatic brain injury.  J of Head Trauma Rehab . 2001;  16 149-164
    PubMedGoogle Scholar
  • 33 Beca J, Cox P N, Taylor M J. Somatosensory evoked potentials for prediction of outcome in acute severe brain injury.  J Pediatr . 1995;  126 44-49
    PubMedGoogle Scholar
  • 34 Hulihan J F, Syna D R. Electroencephalographic sleep patterns in post-anoxic stupor and coma.  Neurology . 1994;  44 758-760
    PubMedGoogle Scholar
  • 35 Pampigliona G, Chaloner J, Harden A. Transitory ischemia/anoxia in young children and the prediction of quality of survival.  Ann N Y Acad Sci . 1978;  315 281-292
    PubMedGoogle Scholar
  • 36 White L E, Frank L M, Furgiuele T L. Childhood coma: improved prediction of outcome with somatosensory and brainstem auditory evoked potentials (abstract).  Ann Neurol . 1985;  18 417
    PubMedGoogle Scholar
  • 37 Marshall L F. Head injury: recent past, present and future.  Neurosurgery . 2000;  47 546-561
    PubMedGoogle Scholar
  • 38 Feldman Z, Kanter M J, Robertson M J. Effect of head elevation on intracranial pressure, cerebral perfusion, and cerebral blood flow in head injured patients.  J Neurosurg . 1992;  76 207-211
    CrossrefPubMedGoogle Scholar
  • 39 Bruce D A, Raphaely R C, Goldberg A I. Pathophysiology, treatment, and outcome following severe head injury in children.  Child's Brain . 1979;  5 174-191
    PubMedGoogle Scholar
  • 40 Mirski M A, Denchev D I, Schnitzer M S. Comparison between hypertonic saline and mannitol in the reduction of elevated intracranial pressure in a rodent model of acute cerebral injury.  J of Neurosurg Anesthes . 2000;  12 334-344
    PubMedGoogle Scholar
  • 41 Muizelaar J P, van der Poel G H, Li Z C. Pial arteriolar vessel diameter and CO2 reactivity during prolonged hyperventilation in the rabbit.  J Neurosurg . 1988;  69 923-927
    PubMedGoogle Scholar
  • 42 Temkin N R, Dikmen S S, Wilensky A J. A randomized, double-blind study of phenytoin for the prevention of posttraumatic seizures.  N Engl J Med . 1990;  323 497-502
    CrossrefPubMedGoogle Scholar
  • 43 Temkin N R, Dikmen S S, Winn H R. Posttraumatic seizures.  Neurosurg Clin North Am . 1991;  2 425-435
    PubMedGoogle Scholar
  • 44 Douzinas E E, Pitaridis M T, Louris G. Prevention of infection in multiple trauma patients by high-dose intravenous immunoglobulins.  Crit Care Med . 2000;  28 8-15
    PubMedGoogle Scholar
  • 45 Hendrick E B. The use of hypothermia in severe head injuries in childhood.  Arch Surg . 1959;  79 362-364
    PubMedGoogle Scholar
  • 46 Lazorthes G, Capman L. Hypothermia in the treatment of craniocerebral traumatism.  J Neurosurg . 1958;  15 162-167
    PubMedGoogle Scholar
  • 47 Sedzmir C B. Therapeutic hypothermia in cases of head injury.  J Neurosurg . 1959;  16 407-414
    PubMedGoogle Scholar
  • 48 Guyer B, Ellers B. Childhood injuries in the United States.  Am J Dis Child . 1990;  144 649-652
    PubMedGoogle Scholar
  • 49 Boyer M G, Edwards P. Outcome 1 to 3 years after severe traumatic brain injury in children and adolescents.  Injury . 1999;  22 315-320
    PubMedGoogle Scholar
  • 50 Brink J D, Garrett A L, Hale W R. Recovery of motor and intellectual function in children sustaining severe head injuries.  Develop Med Child Neurol . 1970;  12 565-571
    PubMedGoogle Scholar
  • 51 Koskiniemi M, Kyykka T, Nybo T. Long-term outcome after severe brain injury in preschoolers is worse than expected.  Arch Pediatr Adolesc Med . 1995;  149 249-254
    CrossrefPubMedGoogle Scholar
  • 52 Mahoney W J, D'Souza B J, Haller A. Long-term outcome of children with severe head trauma and prolonged coma.  Pediatrics . 1983;  71 756-762
    PubMedGoogle Scholar
  • 53 Tilford J M, Simpson P M, Yeh T S. Variation in therapy and outcome for pediatric head trauma patients.  Crit Care Med . 2001;  29 1056-1061
    PubMedGoogle Scholar
  • 54 Annegers J F, Grabow J D, Kurland K T. The incidence, causes, and secular trends of head injury in Olmstead County, Minnesota, 1935-1994.  Neurology . 1980;  30 912-919
    CrossrefPubMedGoogle Scholar
  • 55 Gross C R, Wolf C, Kunitz S C. Pilot Traumatic Coma Data Bank. In: Dacey RG Jr, Winn HR, Rimel RW, Jane JA, eds. Trauma of the Central Nervous System New York: Raven Press 1985: 19-26
    Google Scholar
  • 56 Van der Sluis K C, Kingma J, Eisma W H. Pediatric polytrauma: short- and long-term outcomes.  J Trauma . 1997;  43 501-506
    PubMedGoogle Scholar
  • 57 Functional Independence Measure. Guide for the Uniform Data Set for Medical Rehabilitation, Version 4.0  Buffalo, NY: SUNY at Buffalo 1993
    Google Scholar
  • 58 Jennett B, Bond M. Assessment of outcome after severe brain damage: a practical scale.  Lancet . 1975;  1 480
    Google Scholar
  • 59 Ewing-Cobbs L, Kramer L, Prasad M. Neuroimaging, physical, and developmental findings after inflicted and noninflicted traumatic brain injury in young children.  Pediatrics . 1998;  102 300-307
    CrossrefPubMedGoogle Scholar
  • 60 Bawden H N, Knights R M, Winogrom H W. Speeded performance following head injury in children.  J Clin Exp Neuropsychol . 1997;  7 39-54
    PubMedGoogle Scholar
  • 61 Kaufmann P M, Fletcher J M, Levin H S. Attention disturbance after pediatric closed head injury.  J Child Neurol . 1993;  8 348-353
    PubMedGoogle Scholar
  • 62 Klonoff H, Low M D, Clark C. Head injuries in children.  J Neurol Neurosurg Psych . 1977;  40 1211-1219
    PubMedGoogle Scholar
  • 63 Levin H S, Culhane K A, Flethcher J M. Dissociation between delayed alternation and memory after pediatric head injury.  J Child Neurol . 1994;  9 81-89
    PubMedGoogle Scholar
  • 64 Winogron H W, Knights R M, Bawden H N. Neuropsychological deficits following head injury in children.  J Clin Neuropsychol . 1984;  6 269-286
    PubMedGoogle Scholar
  • 65 Hotz G, Helm-Estabrooks N, Nelson N W. Development of the Pediatric Test of Brain Injury.  J of Head Trauma Rehab . 2001;  16 426-440
    PubMedGoogle Scholar
  • 66 Mittenberg W, Strauman S. Diagnosis of mild head injury and the postconcussion syndrome.  J of Head Trauma Rehab . 2000;  15 783-791
    PubMedGoogle Scholar
  • 67 Donders J, Strom D. Neurobehavioral recovery after pediatric head trauma.  J of Head Trauma Rehab . 2000;  15 792-803
    PubMedGoogle Scholar
  • 68 Collins M, Grindel S, Lovell M. A relationship between concussion and neuropsychological performance in college football players.  JAMA . 1999;  282 964-970
    CrossrefPubMedGoogle Scholar
  • 69 Master E, Kessels A, Lezak M. Neuropsychological impairment in amateur soccer players.  JAMA . 1999;  282 971-973
    CrossrefPubMedGoogle Scholar
  • 70 Anderson V, Morse S, Klug G. Predicting recovery from head injury in young children.  J Int Neuropsych Soc . 1997;  3 581-591
    PubMedGoogle Scholar
  • 71 Jenny C, Hymel K P, Ritzen A. Analysis of missed cases of abusive head trauma.  JAMA . 1999;  281 621-626
    CrossrefPubMedGoogle Scholar
  • 72 Hahn Y S, Raimondi A J, McLone D G. Traumatic mechanisms of head injury in child abuse.  Childs Brain . 1983;  10 229-241
    PubMedGoogle Scholar
  • 73 Reece R M, Sege R. Childhood head injuries: accidental or inflicted?.  Arch of Ped & Adol Med . 2000;  154 11-15
    PubMedGoogle Scholar
  • 74 Becker H, Gupta B. Recognizing abusive head trauma in children.  JAMA . 1999;  282 1421-1422
    CrossrefPubMedGoogle Scholar