Synlett 2002(7): 1118-1122
DOI: 10.1055/s-2002-32589
LETTER
© Georg Thieme Verlag Stuttgart · New York

Pd/C as a Highly Active Catalyst for Heck, Suzuki and Sonogashira Reactions

Roland G. Heidenreicha, Klaus Köhler*a, Jürgen G. E. Krauterb, Jörg Pietschb
a Anorganisch-chemisches Institut, Technische Universität München, Lichtenbergstraße 4, 85747 Garching bei München, Germany
Fax: +49(89)28913473; e-Mail: klaus.koehler@ch.tum.de;
b Degussa AG, Catalysts & Initiators, Rodenbacher Chaussee 4, 63403 Hanau, Germany
Fax: +49(6181)594691; e-Mail: juergen.krauter@degussa.com;
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Publikationsverlauf

Received 8 April 2002
Publikationsdatum:
07. Februar 2007 (online)

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Abstract

A specially optimized air-stable Pd on activated carbon catalyst is demonstrated to be a highly active (TON up to 36,000), selective and convenient heterogeneous catalyst for CC couplings of aryl halides in Heck, Suzuki, and Sonogashira reactions. The Pd/C catalyst developed allows extremely low Pd concentrations (down to 0.0025 mol% for Heck coupling, 0.005 mol% for Suzuki coupling) and high conversions of aryl bromides within a few hours. Easy and complete Pd separation and recovery is possible.