Semin Neurol 2000; 20(4): 409-418
DOI: 10.1055/s-2000-13173
Copyright © 2000 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Aphasia and the Relationship of Language and Brain

Eleanor M. Saffran
  • Center for Cognitive Neuroscience, Department of Neurology, Temple University School of Medicine, Philadelphia, Pennsylvania
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Publikationsdatum:
03. März 2004 (online)

ABSTRACT

This article provides a brief history of the study of aphasia, along with current data on aphasic syndromes and their localization in the brain as well as information on testing procedures. A brief examination of language from a functional perspective is also provided, as it is difficult to understand the breakdown patterns without an appreciation for the complexities of language processing per se.

REFERENCES

  • 1 Broca P. Sur le siège de la faculté de langage articulé.  Bull Anthropol . 1865;  5 377-393
  • 2 Alexander M P. Aphasia: clinical and anatomic aspects. In: Feinberg TE, Farah MJ, eds. Behavioral Neurology and Neuropsychology New York: McGraw-Hill 1997: 133-150
  • 3 Wernicke C. The aphasic symptom complex: a psychological study on a neurological basis. Breslau: Cohn and Weigert; 1874. Reprinted in Eggert GH, ed. and trans. Wernicke's Works on Aphasia. The Hague: Mouton; 1977
  • 4 Lichtheim C. On aphasia.  Brain . 1885;  7 433-484
  • 5 Caplan D. Neurolinguistics and Linguistic Aphasiology.  Cambridge: Cambridge University Press; 1987
  • 6 Dejerine J J. Contribution a l'étude anatomo-pathologique et clinique des différentes variétés de cecute verbale.  Mem Soc Biol . 1892;  4 61-90
  • 7 Marie P. Révision de la question de l'aphasie: la troisieme convolution frontale gauche nejoue aucun rôle spéciale dans la fonction du langage.  Sem Med (Paris) . 1906;  21 241-247
  • 8 Head H. Aphasia and Kindred Disorders of Speech.  Cambridge: Cambridge University Press; 1926
  • 9 Geschwind N. Disconnection syndromes in animals and man: part I.  Brain . 1965;  88 237-229
  • 10 Geschwind N. Disconnection syndromes in animals and man: part II.  Brain . 1965;  88 585-644
  • 11 Schuell H, Jenkins J J, Carroll J M. Factor analysis of the Minnesota Test for differential diagnosis of aphasia.  J Speech Hear Res . 1962;  5 439-369
  • 12 Mesulam M M. Large scale neurocognitive networks and distributed processing for attention, language and memory.  Ann Neurol . 1990;  28 597-613
  • 13 Bates E, Harris C, Marchman V, Wulfeck B, Kritchevsky M. Production of complex syntax in normal aging and Alzheimer's disease.  Lang Cognitive Processes . 1995;  10 487-544
  • 14 Bird H, Franklin S. Cinderella revisited: a comparison of fluent and non-fluent aphasic speech.  J Neurolinguist . 1996;  9 187-206
  • 15 Kertesz A. Aphasia and Associated Disorders.  New York: Grune & Stratton; 1979
  • 16 Mohr J P, Pessin M S, Finkelstein S. Broca's aphasia: pathological and clinical.  Neurology . 1978;  28 311-324
  • 17 Dronkers N F. A new brain region for coordinating speech articulation.  Nature . 1996;  384 159-161
  • 18 Goodglass H, Kaplan E. The Assessment of Aphasia and Related Disorders.  2nd ed. Philadelphia: Lea & Febiger; 1983
  • 19 Benson D F, Ardila A. Aphasia: A Clinical Perspective.  New York: Oxford University Press; 1996
  • 20 Kertesz A. The Western Aphasia Battery.  New York: Grune & Stratton; 1982
  • 21 Caramazza A. The logic of neuropsychological research and the problem of patient classifi-cation in aphasia.  Brain Lang . 1984;  21 9-20
  • 22 Saffran E M, Marin O SM, Yeni-Komshian G. An analysis of speech perception in word deafness.  Brain Lang . 1976;  3 209-228
  • 23 Caramazza A, Zurif E B. Dissociation of algorithmic and heuristic processes in language comprehension: evidence from aphasia.  Brain Lang . 1976;  3 572-582
  • 24 Linebarger M, Schwartz M F, Saffran E M. Sensitivity to grammatical structure in so-called agrammatic aphasics.  Cognition . 1983;  13 641-662
  • 25 Shallice T, Vallar G. The impairment of auditory-verbal short-term storage. In: Vallar G, Shallice T, eds. Neuropsychological Impairments of Short-Term Memory Cambridge: Cambridge University Press 1990: 11-53
  • 26 Saffran E M, Martin N. Short-term memory impairment and sentence processing: a case study. In: Vallar G, Shallice T, eds. Neuropsychological Impairments of Short-Term Memory Cambridge: Cambridge University Press 1990: 428-447
  • 27 Levelt W JM, Roelofs A, Meyer A S. A theory of lexical access in speech production.  Behav Brain Sci . 1999;  22 1-38
  • 28 Grodzinsky Y. The syntactic characterization of agrammatism.  Cognition . 1984;  16 99-120
  • 29 Berndt R S, Caramazza A. A redefinition of the syndrome of Broca's aphasia: implications for a neuropsychological model of language.  Appl Linguist . 1980;  1 225-278
  • 30 Miceli G, Mazzucchi A, Menn L, Goodglass H. Contrasting cases of Italian agrammatic aphasics without comprehension disorder.  Brain Lang . 1983;  19 56-97
  • 31 Hartsuiker R J, Kolk H HJ. Syntactic facilitation in agrammatic sentence production.  Brain Lang . 1998;  62 221-254
  • 32 Saffran E M, Martin N. Effects of structural priming on sentence production in aphasics.  Lang Cognitive Processes . 1997;  12 877-882
  • 33 Caplan D, Futter C. Assignment of thematic roles to nouns in sentence comprehension by an agrammatic patient.  Brain Lang . 1986;  27 117-134
  • 34 Smith E E, Jonides J, Koeppe R A. Spatial vs. object working memory: PET investigations.  J Cognit Neurosci . 1995;  7 337-356
  • 35 Just M A, Carpenter P A, Keller T A, Eddy W F, Thulborn K R. Brain activation modulated by sentence comprehension.  Science . 1996;  274 114-116
  • 36 Stromswold K, Caplan D, Alpert N, Rauch S. Localization of syntactic comprehension by positron emission tomography.  Brain Lang . 1996;  52 452-473
  • 37 Hahne A, Friederici A D. Electrophysiological evidence for two steps in syntactic analysis: early automatic and late controlled processes.  J Cognit Neurosci . 1999;  11 194-205
  • 38 Linebarger M. Agrammatism as evidence about grammar.  Brain Lang . 1995;  50 52-91
  • 39 Kolk H HJ. A time-based approach to agrammatic production.  Brain Lang . 1995;  50 282-303
  • 40 Miyake A, Carpenter P A, Just M A. A capacity approach to syntactic comprehension disorders: making normal adults perform like aphasic patients.  Cognit Neuropsychol . 1994;  11 671-717
  • 41 Grodzinsky Y. Theoretical Perspectives on Language Deficits.  Cambridge, MA: MIT Press; 1990
  • 42 Berndt R S. Sentence processing in aphasia. In: Sarno M Acquired Aphasia. 3rd ed. New York: Academic Press 1998: 229-267
  • 43 Howard D, Patterson K. Pyramids and palm trees: a test of semantic access from pictures and words.  Bury St. Edmonds, UK: Thames Valley Test Company; 1992
  • 44 Snowden J S, Goulding P J, Neary D. Semantic dementia: a form of circumscribed cerebral atrophy.  Behav Neurol . 1989;  2 167-182
  • 45 Hodges J R, Patterson K, Oxbury S, Funnell E. Semantic dementia: progressive fluent aphasia with temporal lobe atrophy.  Brain . 1992;  115 1783-1806
  • 46 Chertkow H, Bub D, Caplan D. Constraining theories of semantic memory processing: evidence from dementia.  Cognit Neuropsychol . 1992;  9 327-365
  • 47 Breedin S D, Saffran E M, Coslett H B. Reversal of the concreteness effect in a patient with semantic dementia.  Cognit Neuropsychol . 1994;  11 617-660
  • 48 Sirigu A, Duhamel J R, Poncet M. The role of sensorimotor experience in object recognition: a case of multimodal agnosia.  Brain . 1991;  114 2555-2573
  • 49 Saffran E M, Sholl A. Clues to the functional and neural architecture of word meaning. In: Hagoort P, Brown C, eds. Neurocognition of Language Oxford: Oxford University Press 1999: 241-272
  • 50 Paivio A. Dual coding theory: retrospect and current status.  Can J Psycho . 1991;  45 255-287
  • 51 Goodglass H, Hyde M R, Blumstein S E. Frequency, picturability and availability of nouns in aphasia.  Cortex . 1969;  5 104-119
  • 52 Ungerleider L G, Mishkin M. Two visual systems. In: Ingle DJ, Goodale MA, Mansfield RJW, eds. Analysis of Visual Behavior Cambridge, MA: MIT Press 1982: 549-586
  • 53 Saffran E M, Schwartz M F. Of cabbages and things: semantic memory from a neuropsychological perspective: a tutorial review. In: Umilta C, Moscovitch M, eds. Attention and Performance XV: Conscious and Nonconscious Information Processing Cambridge, MA: MIT Press, 1994: 507-536
  • 54 Buxbaum L, Saffran E M. Knowing ``how'' vs. ``what for'': a new dissociation.  Brain Lang . 1998;  65 73-76
  • 55 Allport D A. Distributed memory, modular subsystems and dysphasia. In: Newman SK, Epstein R, eds. Current Perspectives in Dysphasia Edinburgh: Churchill Livingstone 1985: 32-60
  • 56 Vandenberghe R, Price C, Wise R, Josephs O, Frackowiak R SJ. Functional anatomy of a common semantic system for words and pictures.  Nature . 1996;  383 254-256
  • 57 Grafton S T, Fadiga L, Arbib M, Rizzolatti G. Premotor cortex activation during observation and naming of familiar tools.  Neuroimage . 1997;  6 231-236
  • 58 Perani D, Cappa S F, Bettinardi V. Different neural systems for the recognition of animals and man-made tools.  NeuroReport . 1995;  6 1637-1641
  • 59 Martin A, Wiggs C L, Ungerleider L G, Haxby J V. Neural correlates of category-specific knowledge.  Nature . 1996;  379 649-652
  • 60 Hillis A E, Rapp B, Caramazza A. Constraining claims about theories of semantic memory: more on unitary vs. multiple semantics.  Cognit Neuropsychol . 1995;  12 175-186
  • 61 Shallice T. From Neuropsychology to Mental Structure.  Cambridge: Cambridge University Press; 1988
  • 62 Schwartz M F, Saffran E M, Bloch D E, Dell G S. Disordered speech production in aphasic and normal speakers.  Brain Lang . 1994;  47 52-881