CC BY-NC-ND 4.0 · Journal of Gastrointestinal Infections 2023; 13(01): 038-040
DOI: 10.1055/s-0043-1768939
Case Report

Melioidosis Presenting as Splenic Abscess: A Case Report

Pranav S. Kumar
1   Department of Medicine, All India Institute of Medical Sciences, Jodhpur, Jodhpur, Rajasthan, India
,
Chhagan Lal Birda
2   Department of Gastroenterology, All India Institute of Medical Sciences, Jodhpur, Jodhpur, Rajasthan, India
,
Yadav Suresh Chand
1   Department of Medicine, All India Institute of Medical Sciences, Jodhpur, Jodhpur, Rajasthan, India
,
Taruna Yadav
3   Department of Radiology, All India Institute of Medical Sciences, Jodhpur, Jodhpur, Rajasthan, India
,
2   Department of Gastroenterology, All India Institute of Medical Sciences, Jodhpur, Jodhpur, Rajasthan, India
› Author Affiliations

Abstract

Melioidosis is an infectious disease caused by Gram-negative bacilli Burkholderia pseudomallei. Infection is acquired by direct exposure through broken skin, inhalation, or ingestion of the bacterium. Melioidosis has a wide variety of clinical presentations, ranging from an asymptomatic infection or localized cutaneous manifestations at the site of the entry, deep-seated abscess, to multiple organ involvement with sepsis leading to death. Although not uncommon, there is a lack of awareness of its variable presentation leading to a delay in the diagnosis and thus treatment. The diagnosis of melioidosis rests on the culture of the organism from biological samples. Presentation as a splenic abscess is rather rare and a high index of suspicion is needed for the diagnosis. In this article, we report an interesting case of recurrent splenic abscess which was eventually diagnosed to be due to melioidosis.

Ethical Statement

As only anonymized data are being reported, ethical clearance was waived off by the ethics committee. A written and informed consent for publication was taken from the patient before submission of the case report.


Authors' Contribution

Conception and design of the study: A.A., C.L.B.


Generation, collection, assembly, analysis, and/or interpretation of data: P.K., S.Y., T.Y.


Drafting or revision of the manuscript: P.K., S.Y., C.L.B., A.A.


Critical revision of the article for important intellectual content: C.L.B., A.A., T.Y.


Approval of the final version of the manuscript: All the authors approved the final manuscript.


Guarantor of article: A.A.


Data Availability Statement

There is no data associated with this work.




Publication History

Received: 07 February 2023

Accepted: 19 March 2023

Article published online:
22 September 2023

© 2023. Gastroinstestinal Infection Society of India. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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  • References

  • 1 Willcocks SJ, Denman CC, Atkins HS, Wren BW. Intracellular replication of the well-armed pathogen Burkholderia pseudomallei. Curr Opin Microbiol 2016; 29: 94-103
  • 2 Limmathurotsakul D, Golding N, Dance DAB. et al. Predicted global distribution of Burkholderia pseudomallei and burden of melioidosis. Nat Microbiol 2016; 1: 15008
  • 3 Yee KC, Lee MK, Chua CT, Puthucheary SD. Melioidosis, the great mimicker: a report of 10 cases from Malaysia. J Trop Med Hyg 1988; 91 (05) 249-254
  • 4 Lipsitz R, Garges S, Aurigemma R. et al. Workshop on treatment of and postexposure prophylaxis for Burkholderia pseudomallei and B. mallei infection, 2010. Emerg Infect Dis 2012; 18 (12) e2
  • 5 Ross BN, Myers JN, Muruato LA, Tapia D, Torres AG. Evaluating new compounds to treat Burkholderia pseudomallei infections. Front Cell Infect Microbiol 2018; 8: 210