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Semin Musculoskelet Radiol 2020; 24(06): 627-644
DOI: 10.1055/s-0040-1721464
Review Article

Soft Tissue Sarcoma Follow-up Imaging: Strategies to Distinguish Post-treatment Changes from Recurrence

Iris-M. Noebauer-Huhmann
1   Division of Neuroradiology and Musculoskeletal Radiology, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria
,
Snehansh R. Chaudhary
2   Department of Clinical Radiology, Aintree University Hospitals NHS Foundation Trust, Liverpool, United Kingdom
,
Olympia Papakonstantinou
3   2nd Department of Radiology, National University of Athens, “Attikon” Hospital, Athens, Greece
,
Joannis Panotopoulos
4   Department of Orthopedics and Trauma-Surgery, Medical University of Vienna, Vienna, Austria
,
Marc-André Weber
5   Institute of Diagnostic and Interventional Radiology, Pediatric Radiology and Neuroradiology, University Medical Center Rostock, Rostock, Germany
,
Radhesh K. Lalam
6   Department of Radiology, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, United Kingdom
,
Omar M. Albtoush
7   Department of Radiology, University of Jordan, and Department of Radiology, King Hussein Cancer Center, Amman, Jordan
,
Barbara J. Fueger
8   Department of Biomedical Imaging and Image Guided Therapy, Medical University of Vienna, Vienna, Austria
,
Pavol Szomolanyi
9   High Field MR Center, Department of Biomedical Imaging and Image Guided Therapy, Medical University of Vienna, Vienna, Austria
,
Thomas Grieser
10   Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Augsburg, Augsburg, Germany
,
Johan L. Bloem
11   Department of radiology, Leiden University Medical Center, Leiden, The Netherlands
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Erratum: Soft Tissue Sarcoma Follow-up Imaging: Strategies to Distinguish Post-treatment Changes from RecurrenceSemin Musculoskelet Radiol 2020; 24(06): e1-e1
DOI: 10.1055/s-0040-1722295

Abstract

Soft tissue sarcomas encompass multiple entities with differing recurrence rates and follow-up intervals. The detection of recurrences and their differentiation from post-therapeutic changes is therefore complex, with a central role for the clinical radiologist. This article describes approved recommendations. Prerequisite is a precise knowledge of the current clinical management and surgical techniques. We review recurrence rates and treatment modalities. An adequate imaging technique is paramount, and comparison with previous imaging is highly recommended. We describe time-dependent therapy-related complications on magnetic resonance imaging compared with the spectrum of regular post-therapeutic changes. Early complications such as seromas, hematomas, and infections, late complications such as edema and fibrosis, and inflammatory pseudotumors are elucidated. The appearance of recurrences and radiation-associated sarcomas is contrasted with these changes. This systematic approach in follow-up imaging of soft tissue sarcoma patients will facilitate the differentiation of post-therapeutic changes from recurrences.

Keywords

sarcoma - recurrence - aftercare - magnetic resonance imaging - postoperative complications


Publication History

Article published online:
11 December 2020

© 2020. Thieme. All rights reserved.

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