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CC BY-NC-ND 4.0 · Int Arch Otorhinolaryngol 2019; 23(04): e427-e432
DOI: 10.1055/s-0039-1693141
Original Research
Thieme Revinter Publicações Ltda Rio de Janeiro, Brazil

The Influence of Dietary Salt on the Osseointegration of Implants in Aging Rats

Julio Baldisserotto 
1   Faculty of Dentistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil
2   Postgraduation Program of Health Technology Assessment, Grupo Hospitalar Conceição, Porto Alegre, RS, Brazil
,
Dalva Maria Pereira Padilha
1   Faculty of Dentistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil
,
José Miguel Amenábar
3   Faculty of Dentistry, Sector of Health Sciences, Universidade Federal do Parana, Curitiba, PR, Brazil
› Author Affiliations
Further Information

Publication History

23 November 2018

23 May 2019

Publication Date:
22 October 2019 (online)

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Abstract

Introduction The bone-implant interface has been studied extensively, but only few papers focused on the nutritional aspects that may affect bone quality, especially salt intake.

Objective To study the osseointegration of implants in salt-loaded rats with low mineral bone content.

Methods A total of 60 4-month-old male rats were divided in 2 groups (n = 30), being these groups divided in 2 periods, (2 and 4 months). The control group received a normal diet, while the test group received a diet supplemented with 1% sodium chloride (NaCl). Implants were placed in the tibia of both groups. A total of 15 animals of each group were sacrificed at the 2nd month of the experiment, while the remaining animals were sacrificed at the 4th month.

Results No statistically significant difference was found in food intake between the groups on any experimental period, but a statistically significant difference was found in the liquid intake in the saline group in both periods. For all groups, osseointegration was observed in both groups. The mean percentage of osseointegration in the cortical bone, in the trabecular bone, and in the total osseointegrated surface between the control (46.38 ± 16.17%) and saline (49.13 ± 11.52%) groups at 2 months was not statistically different (p = 0.61). The total osseointegration areas of the control (53.98 ± 12.06%) and saline (51.40 ± 13.01%) groups at the 4th month of the study were not statistically (p = 0.61).

Conclusion Ingestion of salt did not affect directly the osseointegration process during the period of the experiment. The results suggest that mineral losses may not affect the achievement of good osseointegration in aging rats.

Keywords

osseointegration - sodium chloride - bone density - bone-implant interface
 

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