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DOI: 10.1055/s-0038-1632292
Influence of Blood Viscosity on Circulatory Parameters Determined by First-Pass Radionuclide Angiocardiography in Cor pulmonale
Einfluss der Blutviskosität auf die Kreislaufparameter bestimmt durch First-Pass-Radionuklid-Angiokardiographie in Cor pulmonalePublication History
Received:
07 June 1993
26 July 1993
Publication Date:
03 February 2018 (online)
![](https://www.thieme-connect.de/media/10.1055-s-00034924/199306/lookinside/thumbnails/10-1055-s-0038-1632292_de-1.jpg)
Summary
First-pass radionuclide angiocardiography (FPRNA) with 99mTc-albumin was performed in 19 patients with cor pulmonale. Pulmonary circulation time (PCT), mean transit time (MTT), pulmonary stagnation index (PSI) were calculated from the time-activity curves for the estimation of cardiopulmonary circulation. Whole blood viscosity (WBV), plasma viscosity (PV) and hematocrit (HTC) were also measured on the same day. Significant prolongation of all parameters was observed (WBW: 5,04 ± 1.19 mPas; PV: 1,36 ± 0,17 mPas; HTC: 47,6 ±2,37%; PCT: 7,10 ± 2,15 s; MTT: 9,33 ±4,11 s; PSI: 1,30 ±0,37) in patients with cor pulmonale. Significant positive correlations were found between PCT and WBV (r = 0,552; 0,001 <P <0.01), MTT and WBV (r = 0,34; P <0,05), furthermore between PCT and HTC (r = 0,356; P <0,05). The results suggest that hemorheological parameters may influence the results of FPRNA, therefore, they should be determined in addition to the radionuclide study.
Zusammenfassung
Die First-Pass Untersuchung (FPRNA) mit 99mTc-Albumin wurde bei 19 Patienten mit Cor pulmonale durchgeführt. Pulmonale Zirkulationszeit (PCT), »mean transit« Zeit (MTT), pulmonaler Rest Index (PSI) wurden ermittelt aus den Zeit-Aktivitätskurven zur Einschätzung des kardiopulmonalen Durchflusses. Vollblut-Viskosität (WBV), Plasma-Viskosität (PV) und Hämatokrit (HTC) wurden am selben Tag gemessen. Bezeichnend für Patienten mit Cor pulmonale war eine typische Vergrößerung aller Parameter (WBV: 5,04 ± 1,19 mPAS; PV: 1,36 ± 0,17 mPAS; HTC: 47,6±2,37%; PCT: 7,10±2,15s; MTT: 9,33 ±4,11 s; PSI: 1,30 ±0,37). Verwertbare Korrelationen wurden zwischen PCT und WBV (r = 0,552; 0,001 <p <0,01), MTT und WBV (r = 0,34; p <0,05) sowie zwischen PCT und HTC (r = 0,356; p <0,05) gefunden. Die Resultate zeigen, daß hämorheologische Parameter einen Einfluß auf die Werte der FPRNA haben. Deswegen sollten diese Bestimmungen stets zusammen mit der FPRNA durchgeführt werden.
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