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Synthesis 2015; 47(17): 2641-2646
DOI: 10.1055/s-0034-1380752
DOI: 10.1055/s-0034-1380752
paper
Palladium-Catalyzed Carbonylative Synthesis of N-Benzoylindoles with Mo(CO)6 as the Carbon Monoxide Source
Further Information
Publication History
Received: 12 February 2015
Accepted after revision: 16 April 2015
Publication Date:
28 May 2015 (online)
Abstract
A mild and carbon monoxide gas-free palladium-catalyzed aminocarbonylation of indole has been developed for the synthesis of N-benzoylindoles. This method uses Mo(CO)6 as a convenient CO-precursor and BuPAd2 as the ligand. A number of substituents on the aryl bromide species is tolerated under the presented conditions and gave the desired products in up to excellent yields.
Key words
benzoylindole - aminocarbonylation - palladium catalyst - molybdenum hexacarbonyl - indoleSupporting Information
- Supporting information for this article is available online at http://dx.doi.org/10.1055/s-0034-1380752.
- Supporting Information
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