Asymmetric Organocatalytic Synthesis of Spiro-cyclopropaneoxindoles

Abstract

Straightforward cascade reactions for the synthesis of spiro-cyclopropaneoxindoles are described. The target compounds are obtained in high yields and in good enantio- and diastereoselectivities via hydrogen bonding or iminium catalysis.

Key words

spiro compounds - organocatalysis - oxindoles - 3-chlorooxindoles - asymmetric synthesis

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