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DOI: 10.1055/s-0029-1186031
© Georg Thieme Verlag KG Stuttgart · New York
New Carvotanacetone Derivatives from Sphaeranthus africanus
Publikationsverlauf
received March 10, 2009
revised July 8, 2009
accepted July 10, 2009
Publikationsdatum:
10. August 2009 (online)
![](https://www.thieme-connect.de/media/plantamedica/201002/lookinside/thumbnails/10.1055-s-0029-1186031-1.jpg)
Abstract
The dichloromethane extract of the air-dried leaves of Sphaeranthus africanus afforded four new carvotanacetone derivatives (1, 2, 3a, and 3b). Their structures were elucidated by extensive 1D and 2D NMR spectroscopy. Compounds 1–3 exhibited antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa and antifungal activity against Candida albicans, Trichophyton mentagrophytes and Aspergillus niger.
Key words
Sphaeranthus africanus - Asteraceae - carvotanacetone derivatives - antimicrobial
References
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Prof. Dr. Consolacion Y. Ragasa
Chemistry Department and Center for Natural Sciences and Ecological Research
De La Salle University
2401 Taft Avenue
1004 Manila
Phillipines
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