Planta Med 2002; 68(1): 64-65
DOI: 10.1055/s-2002-19868
Letter

© Georg Thieme Verlag Stuttgart · New York

Radical Scavengers from the Entomogenous Deuteromycete Beauveria amorpha

Fenglin Hu1, 2, 4 , Karen Schmidt1, 4 , Stefka Stoyanova1 , Li Zengzhi2 , Udo Gräfe3 , Matthias Hamburger1
  • 1Institute of Pharmacy, Friedrich-Schiller-University, Jena, Germany
  • 2Research Center on Entomogenous Fungi, Anhui Agricultural University, Hefei, People’s Republic of China
  • 3Hans-Knöll-Institute for Natural Products Research, Jena, Germany
  • 4Equal contribution by both authors
Weitere Informationen

Publikationsverlauf

January 8, 2001

April 28, 2001

Publikationsdatum:
31. Januar 2002 (online)

Abstract

The culture medium of Beauveria amorpha Hohn. exhibited strong radical scavenging properties. Activity-directed fractionation assisted by a radical scavenging assay on TLC afforded two active compounds which were identified as 6-methyl-2,4-dihydroxyphenyl 4-O-methyl-β-D-glucopyranoside (1) and (-)-terredionol (2). Compound 1 displays radical scavenging and lipid peroxidation inhibitory activity comparable to those of Trolox™C, ascorbic acid or quercetin.

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Prof. Dr. Matthias Hamburger

Institute of Pharmacy

Friedrich-Schiller-University Jena

Semmelweisstraße 10

07743 Jena

Germany

eMail: B7HAMA@rz.uni-jena.de

Fax: +49 (0) 3641 949842

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