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Synthesis 1990; 1990(12): 1114-1116
DOI: 10.1055/s-1990-27106
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5(4H)-Oxazolones as Dienophiles in the Synthesis of 2-Amino-2-bicycloalkanecarboxylic Acids

C. Cativiela* , J. A. Mayoral, A. Avenoza, M. Gonzalez, M. A. Roy
  • *Department of Organic Chemistry, Instituto de Ciencia de los Materiales de Aragón, Universidad de Zaragoza, CSIC, ES-50009 Zaragoza, Spain
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Publication Date:
02 May 2002 (online)

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The application of 2-phenyl-4-benzylidene-5(4H)-oxazolone (1) as a dienophile in the synthesis of 2-amino-2-bicycloalkanecarboxylic acids is described. The influence of different Lewis acids and the reaction conditions are discussed.

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