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Int J Sports Med 2022; 43(03): 286-287
DOI: 10.1055/a-1754-3323
Letter to the Editor

Letter to the Editor on: “The Effects of Physical Exercise on Tumor Vasculature: Systematic Review and Meta-Analysis.”

C. Seet-Lee
1   Faculty of Medicine and Health, University of Sydney, Camperdown, Australia
2   Charles Perkins Centre, University of Sydney, Camperdown, Australia
,
H. Morahan
1   Faculty of Medicine and Health, University of Sydney, Camperdown, Australia
2   Charles Perkins Centre, University of Sydney, Camperdown, Australia
,
J. Yee
1   Faculty of Medicine and Health, University of Sydney, Camperdown, Australia
2   Charles Perkins Centre, University of Sydney, Camperdown, Australia
3   Centre for Medical Psychology & Evidence-based Decision-making, School of Psychology, The University of Sydney, Camperdown, Australia
,
KM. Edwards
1   Faculty of Medicine and Health, University of Sydney, Camperdown, Australia
2   Charles Perkins Centre, University of Sydney, Camperdown, Australia
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Comment on:

The Effects of Physical Exercise on Tumor Vasculature: Systematic Review and Meta-analysisInt J Sports Med 2021; 42(14): 1237-1249
DOI: 10.1055/a-1533-1876

Dear Editor,

We read with interest the recent article “The Effects of Physical Exercise on Tumor Vasculature: Systematic Review and Meta-analysis” [1] and after careful appraisal and consideration we feel that some aspects of the data and analysis warrant further review. The study reported some promising results, namely that both chronic and acute exercise appear to improve intratumoral vascularisation in animal models. This is an important finding given increased vascularisation through tumor modulation may have the potential to improve chemotherapy delivery and efficacy [2]. However, after conducting further investigations, we query several details in the data extraction and analysis decision-making that we believe impact the conclusions of this article.



Publication History

Article published online:
01 March 2022

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