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CC BY-NC-ND 4.0 · Endosc Int Open 2017; 05(03): E165-E171
DOI: 10.1055/s-0042-119948
Original article
Eigentümer und Copyright ©Georg Thieme Verlag KG 2017

Endoscopic ultrasound-guided tissue sampling of small subepithelial tumors of the upper gastrointestinal tract with a 22-gauge core biopsy needle

Christoph Schlag
1   II. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany
,
Christoph Menzel
1   II. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany
,
Manuela Götzberger
2   Gastroenterologie, Klinikum Freising, Akademisches Lehrkrankenhaus der Technischen Universität München, Freising, Germany
,
Simon Nennstiel
1   II. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany
,
Peter Klare
1   II. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany
,
Stefan Wagenpfeil
3   Institut für Medizinische Biometrie, Epidemiologie und Medizinische Informatik, Universität des Saarlandes, Campus Homburg, Homburg, Germany
,
Roland M. Schmid
1   II. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany
,
Gregor Weirich   *
4   Institut für Allgemeine Pathologie und Pathologische Anatomie, Technische Universität München, Munich, Germany
,
Stefan von Delius   *
1   II. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany
› Author Affiliations
Further Information

Publication History

submitted 18 May 2016

accepted after revision 13 September 2016

Publication Date:
13 March 2017 (online)

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Abstract

Background and study aims The optimal approach to small subepithelial tumors (SETs) of the upper gastrointestinal tract remains inconclusive. The aim of this study was to evaluate endoscopic ultrasound-guided fine needle biopsy (EUS-FNB) for less invasive tissue sampling of small SETs of the upper gastrointestinal tract.

Patients and methods In this prospective observational study patients with small ( ≤ 3 cm) SETs of the upper gastrointestinal tract were eligible and underwent EUS-FNB with a 22-gauge core biopsy needle. The main outcome measure was the diagnostic yield. The number of obtained core biopsies was also assessed.

Results Twenty patients were included. The mean SET size was 16 mm (range 10 – 27 mm). EUS-FNB was technically feasible in all cases and no complications were observed. The diagnostic yield was 75 %. Core biopsy specimens were obtained in only 25 % of cases.

Conclusion EUS-FNB with a 22-gauge core biopsy needle of small SETs can achieve a definite diagnosis in the majority of cases. However, because core samples cannot regularly be obtained, EUS-FNB seems not to be convincingly superior to standard EUS-FNA in this setting

* equally contributed


 

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