TY - JOUR AU - Jin, Can; Zhang, Xun; Sun, Bin; Yan, Zhiyang; Xu, Tengwei TI - Iron-Catalyzed Regioselective Decarboxylative Alkylation of Coumarins and Chromones with Alkyl Diacyl Peroxides SN - 0936-5214 SN - 1437-2096 PY - 2019 JO - Synlett JF - Synlett LA - EN VL - 30 IS - 13 SP - 1585 EP - 1591 ET - 2019/06/26 DA - 2019/07/30 KW - coumarins KW - chromones KW - C–C bond KW - iron-catalyzed KW - decarboxylation AB - A facile iron-catalyzed decarboxylative radical coupling of alkyl diacyl peroxides with coumarins or chromones has been developed, affording a highly efficient approach to synthesize a variety of α-alkylated coumarins and β-alkylated chromones. The reaction proceeded smoothly without adding any ligand or additive and provided the corresponding products containing a wide scope of functional groups in moderate to excellent yields. This protocol was highlighted by its high regioselectivity, readily available starting materials, and operational simplicity. PB - © Georg Thieme Verlag DO - 10.1055/s-0037-1611864 UR - http://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0037-1611864 ER -