TY - JOUR AU - Blei, Francine TI - Medical Management of Vascular Anomalies SN - 0736-6825 SN - 1098-8793 PY - 2012 JO - Facial Plast Surg JF - Facial Plastic Surgery LA - EN VL - 28 IS - 06 SP - 575 EP - 583 DA - 2012/11/27 KW - vascular anomalies KW - hemangioma KW - vascular malformation AB - The term “vascular anomalies” embraces a spectrum of medical conditions characterized by abnormal growth or development of blood and/or lymphatic vessels. Patient management is frequently provided in a multidisciplinary team approach, as there are many facets to evaluation and treatment. Clinical and basic research during the past decade has enhanced our knowledge, providing insight into possible etiologies, associated genetic mutations, cellular mechanisms modulating the development, and natural history of these disorders. Concomitantly, new therapeutic agents have been identified, which has transformed patient management. In this review, a brief overview of the field including an update in basic research is presented, followed by a discussion of current therapies and their purported mechanism of action. PB - Thieme Medical Publishers DO - 10.1055/s-0032-1329932 UR - http://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0032-1329932 ER -