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Journal of Pediatric Epilepsy 2018; 07(04): 123-135
DOI: 10.1055/s-0039-1677717
Review Article
Georg Thieme Verlag KG Stuttgart · New York

Impact of Rolandic Epilepsy on Language, Cognitive, and Behavioral Functioning in Children: A Review

Angie Premchand
1   Department of Neurolinguistics, University of Groningen, Groningen, The Netherlands
,
Wim Tops
1   Department of Neurolinguistics, University of Groningen, Groningen, The Netherlands
2   Department of Neurolinguistics and CLCG, University of Groningen, Groningen, The Netherlands
› Author Affiliations
Further Information

Publication History

26 September 2018

26 November 2018

Publication Date:
17 January 2019 (online)

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Abstract

The objective of this narrative review was to investigate how the clinical aspects, such as age-at-onset, epilepsy duration, centrotemporal spikes, spike location, and seizure frequency, affect various domains of language, cognition, and behavior in children with benign childhood epilepsy. Data were collected using various research databases, including Wiley Online Library, PubMed Central, Elsevier ClinicalKey, and Springer Complete Journals. Keywords such as “Benign Childhood Epilepsy” or “BECTS and language impairment” were used among other terms. Case reports, meta-analyses, and reviews were excluded. Children with benign childhood epilepsy are mainly impaired in semantic processing (receptive language), working memory, attention/inhibitory control, complex visuospatial skills, and social skills. Functional magnetic resonance imaging reveals not only structural abnormalities, but also alterations in language, sensorimotor, attentional, and social networks, suggesting long-term consequences. It so seems that the occurrence of centrotemporal spikes (with or without seizures), especially at a young age (below 6 years) and for an extended period of time, is the most meaningful contributor to the language, cognitive, and behavioral deficits in benign childhood epilepsy with centrotemporal spikes (BECTS), while the distribution of centrotemporal spikes (left, right, bilateral) seems of only little significance.

Keywords

BECTS - neuropsychological - children
 

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