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Thromb Haemost 1991; 65(01): 087-095
DOI: 10.1055/s-0038-1647460
Original Article
Schattauer GmbH Stuttgart

Blood Flow Stasis Induced by cw-Nd: YAG Laser Irradiation: Comparative Morphology of Mesenteric and Choroidal Vessels in Pigmented Rabbits

E van der Zypen
*   The Institute of Anatomy, University of Bern, Inselspital, Bern, Switzerland
,
C England
*   The Institute of Anatomy, University of Bern, Inselspital, Bern, Switzerland
,
F Fankhauser
**   The University Eye Clinic, Inselspital, Bern, Switzerland
,
S Kwasniewska
**   The University Eye Clinic, Inselspital, Bern, Switzerland
› Author Affiliations
Further Information

Publication History

Received 27 April 1990

Accepted after revision 14 August 1990

Publication Date:
02 July 2018 (online)

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Summary

cw-Nd: YAG laser radiation was effective in producing blood flow stasis within arteries (35 – 40 μm in diameter) of pigmented rabbit mesentery (beam spot size: 80 μm; fluence :2 × 104 J cm−2) and choroid (beam spot size : 200 μm; fluence: 6 × 102 J cm−2) However, the mechanism by which this was achieved differed in each case, and depended upon the energy absorbing structures present in the irradiated tissue. In non-pigmented tissue, such as the mesentaty, haemoglobin represents the primary absorption centre, and the temperature attained within the vessel lumen (as inferred from morphological changes) is sufficient to denature plasma proteins, in particular fibrinogen, which consequently occlude the vessel lumen and arrest bleeding. In pigmented tissue, such as the choroid, melanocyte granules represent the primary absorption centre, which is thus shifted from the vessel lumen to the stroma. The temperature rise achieved within the vessel lumen is consequently loweq as evidenced by the absence of plasma protein denaturation. Blood flow stasis nonetheless occurs, but is triggered according to the normal haemostatic mechanism.

 

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