Pd-Catalyzed C–H Silylation Reactions with Disilanes

Abstract

Pd-catalyzed C–H silylation reactions remain underdeveloped. General strategies usually rely on the use of complex bidentate directing groups. C,C-Palladacycles exhibit extremely high reactivity towards hexamethyldisilane and can be disilylated very efficiently. The C,C-palladacycles are prepared through halide-directed C–H activation. This account introduces Pd-catalyzed C–H silylation reactions with di­silanes as the silyl source, and is focused on studies on the silylation of C,C-palladacycles.

1 Introduction and Background

2 Allylic C–H Silylation Reaction

3 Coordinating-Ligand-Directed C–H Silylation Reaction

4 Disilylation of C(sp²),C(sp²)-Palladacycles That are Generated by C(sp²)–H activation

5 Disilylation of C(sp²),C(sp³)-Palladacycles That are Generated by C(sp³)–H Activation

6 Disilylation of C,C-Palladacycles That are Generated through Domino Processes

7 Summary and Outlook

Key words

silylation - palladacycles - palladium - C–H activation - halides

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