DOI: 10.1055/s-00035024

Thrombosis and Haemostasis

Issue 12 · Volume 100 · 2008 DOI: 10.1055/s-008-36049

Editorial Focus

955
Tay, Kok Hoon; Lane, Deirdre A.; Lip, Gregory Y. H.: Bleeding risks with combination of oral anticoagulation plus antiplatelet therapy: Is clopidogrel any safer than aspirin when combined with warfarin?
958
Wada, Hideo; Hatada, Tsuyoshi: Difference between sepsis and trauma diagnosed as sensitive diagnostic criteria for disseminated intravascular coagulation
960
Corsonello, Andrea; Corica, Francesco: Leptin, obesity and platelet responsiveness: Another piece in the puzzle
962
Shantsila, Eduard; Lip, Gregory Y. H.: Predicting thrombotic events: Creating a complex approach for a complex condition

Theme Issue Editorial

965
Kietzmann, Thomas; Andreasen, Peter: Plasminogen activator inhibitor-1 (PAI-1): A molecule at the crossroads to cell survival or cell death

Theme Issue Article

969
Kruithof, Egbert K. O.: Regulation of plasminogen activator inhibitor type 1 gene expression by inflammatory mediators and statins
976
Samarakoon, Rohan; Higgins, Paul J.: Integration of non-SMAD and SMAD signaling in TGF-β1-induced plasminogen activator inhibitor type-1 gene expression in vascular smooth muscle cells
984
Diebold, Isabel; Kraicun, Damir; Bonello, Steve; Görlach, Agnes: The ‘PAI-1 paradox’ in vascular remodelling
992
Dimova, Elitsa Y.; Kietzmann, Thomas: Metabolic, hormonal and environmental regulation of plasminogen activator inhibitor-1 (PAI-1) expression: Lessons from the liver
1007
Nagamine, Yoshikuni: Transcriptional regulation of the plasminogen activator inhibitor type 1 – with an emphasis on negative regulation
1014
Soeda, Shinji; Koyanagi, Satoru; Kuramoto, Yukako; Kimura, Masahiko; Oda, Masatoshi; Kozako, Tomohiro; Hayashida, Satoru; Shimeno, Hiroshi: Anti-apoptotic roles of plasminogen activator inhibitor-1 as a neurotrophic factor in the central nervous system
1021
Diebold, Isabel; Djordjevic, Talija; Hess, John; Görlach, Agnes: Rac-1 promotes pulmonary artery smooth muscle cell proliferation by upregulation of plasminogen activator inhibitor-1: Role of NFκB-dependent hypoxia-inducible factor-1α transcription
1029
Balsara, Rashna D.; Ploplis, Victoria A.: Plasminogen activator inhibitor-1: The double-edged sword in apoptosis
1037
Schneider, David J.; Chen, Yabing; Sobel, Burton E.: The effect of plasminogen activator inhibitor type 1 on apoptosis
1041
Lademann, Ulrik A.; Rømer, Maria Unni: Regulation of programmed cell death by plasminogen activator inhibitor type 1 (PAI-1)

Clinical Focus

1047
Levi, Marcel; Hovingh, Kees: Bleeding complications in patients on anticoagulants who would have been disqualified for clinical trials

Review Article

1052
Beinema, Maarten; Brouwers, Jacobus R. B. J.; Schalekamp, Tom; Wilffert, Bob: Pharmacogenetic differences between warfarin, acenocoumarol and phenprocoumon

Blood Coagulation, Fibrinolysis and Cellular Haemostasis

1058
Jeimy, Samira B.; Fuller, Nola; Tasneem, Subia; Segers, Kenneth; Stafford, Alan R.; Weitz, Jeffrey I.; Camire, Rodney M.; Nicolaes, Gerry A. F.; Hayward, Catherine P. M.: Multimerin 1 binds factor V and activated factor V with high affinity and inhibits thrombin generation
1068
Steppich, Birgit A.; Seitz, Isabell; Busch, Gabi; Stein, Andreas; Ott, Ilka: Modulation of tissue factor and tissue factor pathway inhibitor-1 by neutrophil proteases
1076
Schalekamp, Tom; Klungel, Olaf H.; Souverein, Patrick C.; de Boer, Anthonius: Effect of oral antiplatelet agents on major bleeding in users of coumarins
1084
Smalberg, Jasper H.; Spaander, Manon V. M. C. W.; Jie, Kon-Siong G.; Pattynama, Peter M. T.; van Buuren, Henk R.; van den Berg, Bart; Janssen, Harry L. A.; Leebeek, Frank W. G.: Risks and benefits of transcatheter thrombolytic therapy in patients with splanchnic venous thrombosis
1089
Siebenhofer, Andrea; Rakovac, Ivo; Kleespies, Caroline; Piso, Brigitte; Didjurgeit, Ulrike; for the SPOG 60+ Study Group: Self-management of oral anticoagulation reduces major outcomes in the elderly
1099
Kushimoto, Shigeki; Gando, Satoshi; Saitoh, Daizoh; Ogura, Hiroshi; Mayumi, Toshihiko; Koseki, Kazuhide; Ikeda, Toshiaki; Ishikura, Hiroyasu; Iba, Toshiaki; Ueyama, Masashi; Eguchi, Yutaka; Otomo, Yasuhiro; Okamoto, Kohji; Endo, Shigeatsu; Shimazaki, Shuji; the Japanese Association for Acute Medicine Disseminated Intravascular Coagulation (JAAM DIC) Study Group: Clinical course and outcome of disseminated intravascular coagulation diagnosed by Japanese Association for Acute Medicine criteria
1106
Spiezia, Luca; Radu, Claudia; Marchioro, Paolo; Bertini, Diana; Rossetto, Valeria; Castelli, Monica; Pagnan, Antonio; Sørensen, Benny; Simioni, Paolo: Peculiar whole blood rotation thromboelastometry (Rotem) profile in 40 sideropenic anaemia patients

Platelets and Blood Cells

1111
Damon, Andrea L.; Scudder, Lesley E.; Gnatenko, Dmitri V.; Sitaraman, Varsha; Hearing, Patrick; Jesty, Jolyon; Bahou, Wadie F.: Altered bioavailability of platelet-derived factor VIII during thrombocytosis reverses phenotypic efficacy in haemophilic mice
1123
Dellas, Claudia; Schäfer, Katrin; Rohm, Ilonka; Lankeit, Mareike; Ellrott, Thomas; Faustin, Vivien; Riggert, Joachim; Hasenfuss, Gerd; Konstantinides, Stavros: Absence of leptin resistance in platelets from morbidly obese individuals may contribute to the increased thrombosis risk in obesity
1130
Baroletti, Steven; Piovella, Chiara; Fanikos, John; Labreche, Matthew; Lin, Jay; Goldhaber, Samuel Z.: Heparin-induced thrombocytopenia (HIT): Clinical and economic outcomes
1136
Gori, Anna Maria; Marcucci, Rossella; Paniccia, Rita; Giusti, Betti; Fedi, Sandra; Antonucci, Emilia; Buonamici, Piergiovanni; Antoniucci, David; Gensini, Gian Franco; Abbate, Rosanna: Thrombotic events in high risk patients are predicted by evaluating different pathways of platelet function

Endothelium and Vascular Development

1146
Fenske, Dominic; Dersch, Katrin; Lux, Cornelia; Zipse, Lisa; Suriyaphol, Prapat; Dragneva, Yolantha; Han, Shan-Rui; Bhakdi, Sucharit; Husmann, Matthias: Enzymatically hydrolyzed low-density lipoprotein modulates inflammatory responses in endothelial cells

Cardiovascular Biology and Cell Signalling

1155
Dragomir, Elena; Manduteanu, Ileana; Calin, Manuela; Gan, Ana Maria; Stan, Daniela; Koenen, Rory Ryan; Weber, Christian; Simionescu, Maya: High glucose conditions induce upregulation of fractalkine and monocyte chemotactic protein-1 in human smooth muscle cells
Online Supplementary Material (PDF) Online Supplementary Material (PDF)

Cellular Proteolysis and Oncology

1166
Fritzsche, Juliane; Simonis, Dirk; Bendas, Gerd: Melanoma cell adhesion can be blocked by heparin in vitro: Suggestion of VLA-4 as a novel target for antimetastatic approaches
1176
Akl, Elie A.; Terrenato, Irene; Barba, Maddalena; Sperati, Francesca; Muti, Paola; Schünemann, Holger J.: Extended perioperative thromboprophylaxis in patients with cancer
Online Supplementary Material (PDF) Online Supplementary Material (PDF)

New Technologies, Diagnostic Tools and Drugs

1181
van den Besselaar, Anton M. H. P.; Witteveen, Evelina; van der Meer, Felix J. M.: Influence of haematocrit on international normalised ratio (INR) differences between a whole blood point-of-care coagulation monitor and reference prothrombin time in plasma
1185
Ruppert, Clemens; Mahavadi, Poornima; Wygrecka, Malgorzata; Weaver, Timothy E.; Magdolen, Viktor; Idell, Steven; Preissner, Klaus T.; Seeger, Werner; Günther, Andreas; Markart, Philipp: Recombinant production of a hybrid plasminogen activator composed of surfactant protein B and low-molecular-weight urokinase

Case Report

1193
Di Gennaro, Leonardo; Di Stasi, Carmine; Truglia, Simona; Snider, Francesco; Landolfi, Raffaele: Retrievable filter as an unusual cause of abdominal and lower back pain: A report of an exceptional case
1196
Caputo, Roberto; Pucci, Neri; Mori, Francesca; Secci, Jacopo; Novembre, Elio; Frosini, Riccardo: Long-term efficacy of surgical removal of pseudomembranes in a child with ligneous conjunctivitis treated with plasminogen eyedrops

Letters to the Editor

1199
Kotlín, Roman; Reicheltová, Zuzana; Sobotková, Alžbòta; Suttnar, Jiří; Salaj, Peter; Pospíšilová, Dagmar; Smejkal, Petr; Chrastinová, Leona; Dyr, Jan E.: Three cases of abnormal fibrinogens: Šumperk (Bβ His67Leu), Uniãov (Bβ Gly414Ser), and Brno (γArg275His)
1201
Frankhauser, Pascal; Baranyai, Reka; Ahrens, Thorben; Schloss, Patrick; Deuschle, Michael; Lederbogen, Florian: Platelet surface P-selectin expression is highly correlated with serotonin transporter density in human subjects
1203
Nijkeuter, Mathilde; Tick, Lidwine W.; Sohne, Maaike; Kruip, Marieke J. H. A.; Buller, Harry R.; Leebeek, Frank W. G.; Kramer, Mark H. H.; Klok, Frederikus A.; Prins, Martin H.; Huisman, Menno V.; the Christopher Study Investigators; on behalf of: Excluding pulmonary embolism without imaging tests – Can our diagnostic algorithm be optimized?
1207
Långström, Satu; Rautiainen, Paula; Mildh, Leena; Peltola, Kaija; Wartiovaara-Kautto, Ulla; Heikinheimo, Markku; Petäjä, Jari: Fresh frozen plasma does not reduce in vivo thrombin formation after neonatal cardiopulmonary bypass surgery
1209
Girard, Philippe; Suresh, Ratana; Cosserat, Julie; Czitrom, Daniel; Le Guillou, Jean-Luc; Leblanc, Isabelle; Strauss, Christiane; Stern, Jean-Baptiste: Futile D-dimer testing in hospitalized patients - Description, interpretation, improvements
1211
Navarro-Núñez, Leyre; Roldán, Vanessa; Lozano, María Luisa; Rivera, José; Marin, Francisco; Vicente, Vicente; Martínez, Constantino: TUBB1 Q43P polymorphism does not protect against acute coronary syndrome and premature myocardial infarction
1213
Onundarson, Pall T.; Gudmundsdottir, Brynja R.; Marder, Victor J.: On the significance of marginally low von Willebrand factor

Editorial

1215
Preissner, Klaus T.: Editor´s choice articles 2006–2008