DOI: 10.1055/s-00035024

Thrombosis and Haemostasis

Issue 03 · Volume 99 · 2008 DOI: 10.1055/s-007-35416

Editorial Focus

457
Blat, Yuval; Seiffert, Dietmar: A renaissance for the contact system in blood coagulation?
461
Filep, János G.: Perplexity of monocyte responses to C-reactive protein (CRP)
463
Levi, Marcel: A long-awaited small step forward in the management of the post-thrombotic syndrome

Theme Issue Editorial

465
Preissner, Klaus T.: From Molecules to Medicine: New Horizons in Vascular Biology and Thrombosis (Part II)

Theme Issue Article

466
Gachet, Christian: P2 receptors, platelet function and pharmacological implications
473
Clemetson, Kenneth J.; Clemetson, Jeannine M.: Platelet GPIb complex as a target for anti-thrombotic drug development
480
Langer, Harald F.; Gawaz, Meinrad: Platelet-vessel wall interactions in atherosclerotic disease
487
May, Andreas E.; Geisler, Tobias; Gawaz, Meinrad: Individualized antithrombotic therapy in high risk patients after coronary stenting. A double-edged sword between thrombosis and bleeding
494
Wygrecka, Malgorzata; Jablonska, Ewa; Guenther, Andreas; Preissner, Klaus T.; Markart, Philipp: Current view on alveolar coagulation and fibrinolysis in acute inflammatory and chronic interstitial lung diseases

Review Article

502
Hull, Russell D.: Treatment of pulmonary embolism: The use of low-molecularweight heparin in the inpatient and outpatient settings

Blood Coagulation, Fibrinolysis and Cellular Haemostasis

511
Bukys, Michael A.; Orban, Tivadar; Kim, Paul Y.; Nesheim, Michael E.; Kalafatis, Michael: The interaction of fragment 1 of prothrombin with the membrane surface is a prerequisite for optimum expression of factor Va cofactor activity within prothrombinase
523
Guella, Ilaria; Soldà, Giulia; Spena, Silvia; Asselta, Rosanna; Ghiotto, Rossella; Tenchini, Maria Luisa; Castaman, Giancarlo; Duga, Stefano: Molecular characterization of two novel mutations causing factor XI deficiency: A splicing defect and a missense mutation responsible for a CRM+ defect
531
Melo, Fábio R.; Mourão, Paulo A. S.: An algal sulfated galactan has an unusual dual effect on venous thrombosis due to activation of factor XII and inhibition of the coagulation proteases
539
Fonseca, Roberto J. C.; Oliveira, Stephan-Nicollas M. C. G.; Melo, Fábio R.; Pereira, Maria G.; Benevides, Norma M. B.; Mourão, Paulo A. S.: Slight differences in sulfation of algal galactans account for differences in their anticoagulant and venous antithrombotic activities
546
Arcelus, Juan Ignacio; Monreal, Manuel; Caprini, Joseph A.; Guisado, Javier Gutiérrez; Soto, Mª José; Núñez, Manuel Jesús; Alvárez, Juan Carlos; the RIETE investigators: Clinical presentation and time-course of postoperative venous thromboembolism: Results from the RIETE Registry

Platelets and Blood Cells

552
Guchhait, Prasenjit; Shrimpton, Corie N.; Honke, Koichi; Rumbaut, Rolando E.; Lopez, Jose A.; Thiagarajan, Perumal: Effect of an anti-sulfatide single-chain antibody probe on platelet function
558
Hanriot, Didier; Bello, Gaëlle; Ropars, Armelle; Seguin-Devaux, Carole; Poitevin, Gaël; Grosjean, Sandrine; Latger-Cannard, Vèronique; Devaux, Yvan; Zannad, Faiez; Regnault, Vèronique; Lacolley, Patrick; Mertes, Paul-Michel; Hess, Ketsia; Longrois, Dan: C-reactive protein induces pro- and anti-inflammatory effects, including activation of the liver X receptor α, on human monocytes

Wound Healing and Inflammation/Infection

570
Hochart, Helene; Jenkins, Vincent P.; Preston, Roger J. S.; Smith, Owen P.; White, Barry; O’Donnell, James: Concentration-dependent roles for heparin in modifying liopolysaccharide-induced activation of mononuclear cells in whole blood

Endothelium and Vascular Development

576
Provençal, Mathieu; Michaud, Marisol; Beaulieu, Édith; Ratel, David; Rivard, Georges-Étienne; Gingras, Denis; Béliveau, Richard: Tissue factor pathway inhibitor (TFPI) interferes with endothelial cell migration by inhibition of both the Erk pathway and focal adhesion proteins
586
Dong, Jing-fei; Cruz, Miguel A.; Aboulfatova, Khatira; Martin, Cecilia; Choi, Hiuwan; Bergeron, Angela L.; Martini, Sheryl R.; Kroll, Michael H.; Kent, Thomas A.: Magnesium maintains endothelial integrity, up-regulates proteolysis of ultra-large von Willebrand factor, and reduces platelet aggregation under flow conditions

Cardiovascular Biology and Cell Signalling

594
Castelnuovo, Augusto Di; Soccio, Manola; Iacoviello, Licia; Evangelista, Virgilio; Consoli, Agostino; Vanuzzo, Diego; Diviacco, Silvia; Carluccio, Marisa; Rignanese, Lucia; Caterina, Raffaele De: The C242T polymorphism of the p22phox component of NAD (P)H oxidase and vascular risk
602
Notø, Ann-Trude With; Mathiesen, Ellisiv Bøgeberg; Østerud, Bjarne; Amiral, Jean; Vissac, Anne Marie; Hansen, John-Bjarne: Increased thrombin generation in persons with echogenic carotid plaques

New Technologies, Diagnostic Tools and Drugs

609
Straub, Andreas; Wendel, Hans Peter; Dietz, Klaus; Schiebold, Daniela; Peter, Karlheinz; Schoenwaelder, Simone M.; Ziemer, Gerhard: Selective inhibition of the platelet phosphoinositide 3-kinase p110β as promising new strategy for platelet protection during extracorporeal circulation
616
Tiede, Andreas; Tait, R. Campbell; Shaffer, Don W.; Baudo, Francesco; Boneu, Bernard; Dempfle, Carl Erik; Horellou, Marie Helene; Klamroth, Robert; Lazarchick, John; Mumford, Andrew D.; Schulman, Sam; Shiach, Caroline; Bonfiglio, Laura J.; Frieling, Johan T. M.; Conard, Jacqueline; Depka, Mario von: Antithrombin alfa in hereditary antithrombin deficient patients: A phase 3 study of prophylactic intravenous administration in high risk situations
623
O’Donnell, Martin J.; McRae, Simon; Kahn, Susan R.; Julian, Jim A.; Kearon, Clive; MacKinnon, Betsy; Magier, Debbie; Strulovich, Carla; Lyons, Theresa; Robinson, Sandra; Hirsh, Jack; Ginsberg, Jeffrey S.: Evaluation of a venous-return assist device to treat severe post-thrombotic syndrome (VENOPTS)

Letters to the Editor

630
Favaloro, Emmanuel J.: von Willebrand disease, type 2B: A diagnosis more elusive than previously thought
632
Casonato, Alessandra; Sartorello, Francesca; Pontara, Elena; Gallinaro, Lisa; Cattini, Maria Grazia: Type 2B-like von Willebrand disease: A creative approach to a difficult diagnosis
634
Albert, Thilo; Egler, Christian; Jakuschev, Stanislav; Schuldenzucker, Ulrike; Schmitt, Alexandra; Brokemper, Olive; Zabe-Kühn, Martin; Hoffmann, Daniel; Oldenburg, Johannes; Schwaab, Rainer: The B-cell epitope of the monoclonal anti-factor VIII antibody ESH8 characterized by peptide array analysis
637
van Werkum, Jochem W.; Topcu, Yasemin; Postma, Sonja; Kelder, Johannes C.; Hackeng, Christian M.; ten Berg, Jurrien M.; Verheugt, Freek W. A.: Effects of diabetes mellitus on platelet reactivity after dual antiplatelet therapy with aspirin and clopidogrel
640
Grandone, Elvira; Colaizzo, Donatella; Tiscia, Giovanni L.; Vergura, Patrizia; Chinni, Elena; Iannaccone, Luigi; Antinolfi, Iole; Guardascione, Maria A.; Margaglione, Maurizio: Venous thrombosis in oral contraceptive users and the presence of the JAK2 V617F mutation
642
Poulou, Loukia S.; Xila, Vassilia; Rokas, George I.; Karianakis, George; Bartzoudis, Dimitrios; Ziakas, Panayiotis D.: Temporal trends in mortality rates from visceral vein thrombosis in paroxysmal nocturnal haemoglobinuria: An optimistic view