DOI: 10.1055/s-00035024

Thrombosis and Haemostasis

Issue 02 · Volume 115 · March 2016 DOI: 10.1055/s-007-35253

Invited Editorial Focus

233
Konstantinides, Stavros V.: Trends in incidence versus case fatality rates of pulmonary embolism: Good news or bad news?

T&Insights

236
Mause, Sebastian F.: Microparticles as intercellular carriers of the microRNA signal: insights for novel diagnostic and therapeutic approaches

T&Images

237
Vergallo, Rocco; Aguirre, Aaron D.; Abtahian, Farhad; Minami, Yoshiyasu; Soeda, Tsunenari; Chatzizisis, Yiannis S.; Croce, Kevin; Jang, Ik-Kyung: Recurrent myocardial infarctions and premature coronary atherosclerosis in a 23-year-old man with antiphospholipid syndrome

Review Article

240
Stefano, Valerio De; Qi, Xingshun; Betti, Silvia; Rossi, Elena: Splanchnic vein thrombosis and myeloproliferative neoplasms: molecular-driven diagnosis and long-term treatment
250
Balduini, Alessandra; Buduo, Christian A. Di; Kaplan, David L.: Translational approaches to functional platelet production ex vivo
257
Weitz, Jeffrey I.; Eikelboom, John: Incorporating edoxaban into the choice of anticoagulants for atrial fibrillation

Coagulation and Fibrinolysis

271
Honickel, Markus; Maron, Benjamin; Ryn, Joanne van; Braunschweig, Till; Cate, Hugo ten; Spronk, Henri M. H.; Rossaint, Rolf; Grottke, Oliver: Therapy with activated prothrombin complex concentrate is effective in reducing dabigatran-associated blood loss in a porcine polytrauma model
285
Sciascia, Savino; Branch, D. Ware; Levy, Roger A.; Middeldorp, Saskia; Pavord, Sue; Roccatello, Dario; Ruiz-Irastorza, Guillermo; Tincani, Angela; Khamashta, Munther; Schreiber, Karen; Hunt, Beverley J.: The efficacy of hydroxychloroquine in altering pregnancy outcome in women with antiphospholipid antibodies
291
Majeed, Ammar; Goldhaber, Samuel Z.; Kakkar, Ajay; Kearon, Clive; Eriksson, Henry; Kreuzer, Jörg; Feuring, Martin; Hantel, Stephan; Friedman, Jeffrey; Schellong, Sebastian; Schulman, Sam: Bleeding events with dabigatran or warfarin in patients with venous thromboembolism
299
Koizume, Shiro; Ito, Shin; Yoshioka, Yusuke; Kanayama, Tomohiko; Nakamura, Yoshiyasu; Yoshihara, Mitsuyo; Yamada, Roppei; Ochiya, Takahiro; Ruf, Wolfram; Miyagi, Etsuko; Hirahara, Fumiki; Miyagi, Yohei: High-level secretion of tissue factor-rich extracellular vesicles from ovarian cancer cells mediated by filamin-A and protease-activated receptors
Online Supplementary Material (PDF) Online Supplementary Material (PDF)

Cellular Haemostasis and Platelets

311
Laffont, Benoit; Corduan, Aurélie; Rousseau, Matthieu; Duchez, Anne-Claire; Lee, Chan Ho C.; Boilard, Eric; Provost, Patrick: Platelet microparticles reprogram macrophage gene expression and function
Online Supplementary Material (PDF) Online Supplementary Material (PDF)
324
Jouni, Rabie; Zöllner, Heike; Khadour, Ahmad; Wesche, Jan; Grotevendt, Anne; Brandt, Sven; Delcea, Mihaela; Krauel, Krystin; Schwertz, Hansjörg; Sachs, Ulrich J.; Greinacher, Andreas; Bakchoul, Tamam: Partially desulfated heparin modulates the interaction between anti-protamine/heparin antibodies and platelets
333
Guglielmini, Giuseppe; Appolloni, Viviana; Momi, Stefania; Groot, Philip G. de; Battiston, Monica; Marco, Luigi de; Falcinelli, Emanuela; Gresele, Paolo: Matrix metalloproteinase-2 enhances platelet deposition on collagen under flow conditions
Online Supplementary Material (PDF) Online Supplementary Material (PDF)

Blood Cells, Inflammation and Infection

344
Pounis, George; Bonaccio, Marialaura; Castelnuovo, Augusto Di; Costanzo, Simona; Curtis, Amalia De; Persichillo, Mariarosaria; Sieri, Sabina; Donati, Maria Benedetta; Cerletti, Chiara; Gaetano, Giovanni de; Iacoviello, Licia: Polyphenol intake is associated with low-grade inflammation, using a novel data analysis from the Moli-sani study
Online Supplementary Material (PDF) Online Supplementary Material (PDF)
353
Rutten, Bert; Roest, Mark; McClellan, Elizabeth A.; Sels, Jan W.; Stubbs, Andrew; Jukema, J. Wouter; Doevendans, Pieter A.; Waltenberger, Johannes; Zonneveld, Anton-Jan van; Pasterkamp, Gerard; Groot, Philip G. de; Hoefer, Imo E.: Platelet density per monocyte predicts adverse events in patients after percutaneous coronary intervention

New Technologies, Diagnostic Tools and Drugs

361
Utne, Kristin Kornelia; Ghanima, Waleed; Foyn, Siv; Kahn, Susan; Sandset, Per Morten; Wik, Hilde Skuterud: Development and validation of a tool for patient reporting of symptoms and signs of the post-thrombotic syndrome
Online Supplementary Material (PDF)
368
Douxfils, Jonathan; Chatelain, Bernard; Chatelain, Christian; Dogné, Jean-Michel; Mullier, François: Edoxaban: Impact on routine and specific coagulation assays
Online Supplementary Material (PDF) Online Supplementary Material (PDF)
382
Collet, Jean-Philippe; Kerneis, Mathieu; Hulot, Jean-Sebastien; O’Connor, Stephen A.; Silvain, Johanne; Mansencal, Nicolas; Brugier, Delphine; Abtan, Jérémie; Barthélémy, Olivier; Vignalou, Jean-Baptiste; Payot, Laurent; Rousseau, Héléne; Vicaut, Eric; Montalescot, Gilles; for the GAMMA investigators: Point-of-care genetic profiling and/or platelet function testing in acute coronary syndrome

Stroke, Systemic or Venous Thromboembolism

392
Regina, Micaela La; Orlandini, Francesco; Marchini, Francesca; Marinaro, Alessia; Bonacci, Rosanna; Bonanni, Paola; Corsini, Francesca; Ceraudo, Anna Maria; Pacetti, Edoarda; Scuotri, Lucia; Costabile, Davide; Dentali, Francesco: Combined assessment of thrombotic and haemorrhagic risk in acute medical patients
Online Supplementary Material (PDF) Online Supplementary Material (PDF)
399
Dentali, Francesco; Ageno, Walter; Pomero, Fulvio; Fenoglio, Luigi; Squizzato, Alessandro; Bonzini, Matteo: Time trends and case fatality rate of in-hospital treated pulmonary embolism during 11 years of observation in Northwestern Italy
Online Supplementary Material (PDF) Online Supplementary Material (PDF)
406
Bruzelius, Maria; Ljungqvist, Maria; Bottai, Matteo; Bergendal, Annica; Strawbridge, Rona J.; Holmström, Margareta; Silveira, Angela; Kieler, Helle; Hamsten, Anders; Lärfars, Gerd; Odeberg, Jacob: F11 is associated with recurrent VTE in women
Online Supplementary Material (PDF) Online Supplementary Material (PDF)
415
Perez-Segura, Pedro; Zamorano-León, José J; Acosta, Daniel; Santos-Sancho, Juana María; Modrego, Javier; Caldés, Trinidad; Hoya, Miguel de la; Díaz-Rubio, Eduardo; Díaz-Millán, Isabel; Heras, Natalia de las; Zalba, Luis Alfonso Rico; Lahera, Vicente; Melander, Olle; López Farré, Antonio: BRCA2 gene mutations and coagulation-associated biomarkers
424
Nisio, Marcello Di; Ageno, Walter; Rutjes, Anne W. S.; Pap, Akos F.; Büller, Harry R.: Risk of major bleeding in patients with venous thromboembolism treated with rivaroxaban or with heparin and vitamin K antagonists
Online Supplementary Material (PDF) Online Supplementary Material (PDF) Online Supplementary Material (xls) Online Supplementary Material (xls)

Atherosclerosis ans Ischaemic Disease

433
Asher, Elad; Fefer, Paul; Sabbag, Avi; Herscovici, Romana; Regev, Ehud; Mazin, Israel; Shlomo, Nir; Zahger, Doron; Atar, Shaul; Hammerman, Haim; Polak, Arthur; Beigel, Roy; Matetzky, Shlomi; for The PLATIS (Platelets and Thrombosis in Sheba) Study Group: Prior chronic clopidogrel therapy is associated with increased adverse events and early stent thrombosis

Atherosclerosis and Ischaemic Disease

439
Chuang, Ya-Wen; Yu, Mei-Ching; Lin, Cheng-Li; Yu, Tung-Min; Shu, Kuo-Hsiung; Huang, Shih-Ting; Kao, Chia-Hung: Risk of peripheral arterial occlusive disease in patients with rheumatoid arthritis
446
Hertle, Elisabeth; Arts, Ilja C. W.; Kallen, Carla J. H. van der; Feskens, Edith J. M.; Schalkwijk, Casper G.; Stehouwer, Coen D. A.; Greevenbroek, Marleen M. J. van: The alternative complement pathway is longitudinally associated with adverse cardiovascular outcomes
Online Supplementary Material (PDF) Online Supplementary Material (PDF)

Letters to the Editor

458
Franchini, Massimo; Mengoli, Carlo; Bonfanti, Carlo; Rossi, Chiara; Lippi, Giuseppe: Genetic determinants of extreme longevity: the role of ABO blood group
461
Ganjam, Goutham Kumar; Chi, Tabughang Franklin; Kietzmann, Thomas; Dimova, Elitsa Y.: Resveratrol: beneficial or not? Opposite effects of resveratrol on hypoxia-dependent PAI-1 expression in tumour and primary cells