DOI: 10.1055/s-00000077

Seminars in Thrombosis and Hemostasis

Issue 05 · Volume 42 · July 2016 DOI: 10.1055/s-006-31987 Controversies in Inherited Bleeding Disorders Guest Editors: Antonio Coppola, MD, Massimo Franchini, MD, and Annarita Tagliaferri, MD.

Preface

459
Coppola, Antonio; Tagliaferri, Annarita; Franchini, Massimo: Controversies in Inherited Bleeding Disorders

463
Tosetto, Alberto: Bleeding Assessment Tools: Limits and Advantages for the Diagnosis and Prognosis of Inherited Bleeding Disorders
471
Lippi, Giuseppe; Franchini, Massimo; Favaloro, Emmanuel J.: Diagnostics of Inherited Bleeding Disorders of Secondary Hemostasis: An Easy Guide for Routine Clinical Laboratories
478
Castaman, Giancarlo; Federici, Augusto B.: Type 2B von Willebrand Disease: A Matter of Plasma Plus Platelet Abnormality
483
Favaloro, Emmanuel J.; Pasalic, Leonardo; Curnow, Jennifer: Type 2M and Type 2A von Willebrand Disease: Similar but Different
498
Saccullo, Giorgia; Makris, Mike: Prophylaxis in von Willebrand Disease: Coming of Age?
507
Castaman, Giancarlo; Eckhardt, Corien; van Velzen, Alice; Linari, Silvia; Fijnvandraat, Karin: Emerging Issues in Diagnosis, Biology, and Inhibitor Risk in Mild Hemophilia A
513
Giangrande, Paul: The Future of Hemophilia Treatment: Longer-Acting Factor Concentrates versus Gene Therapy
518
Berntorp, Erik; Andersson, Nadine G.: Prophylaxis for Hemophilia in the Era of Extended Half-Life Factor VIII/Factor IX Products
526
Mannucci, Pier Mannuccio; Mancuso, Maria Elisa; Santagostino, Elena; Franchini, Massimo: Innovative Pharmacological Therapies for the Hemophilias Not Based on Deficient Factor Replacement
533
Windyga, Jerzy: Is Continuous Low-Dose Prophylaxis Superior to On-Demand Treatment for Patients with Hemophilia?
541
Di Minno, Matteo Nicola Dario; Ambrosino, Pasquale; Quintavalle, Gabriele; Coppola, Antonio; Tagliaferri, Annarita; Martinoli, Carlo; Rivolta, Gianna Franca: Assessment of Hemophilic Arthropathy by Ultrasound: Where Do We Stand?
563
Coppola, Antonio; Marrone, Emiliana; Conca, Paolo; Cimino, Ernesto; Mormile, Rosaria; Baldacci, Erminia; Santoro, Cristina: Safety of Switching Factor VIII Products in the Era of Evolving Concentrates: Myths and Facts
577
Santoro, Cristina; Massaro, Fulvio; Venosi, Salvatore; Capria, Saveria; Baldacci, Erminia; Foà, Roberto; Mazzucconi, Maria Gabriella: Severe Thrombotic Complications in Congenital Afibrinogenemia: A Pathophysiological and Management Dilemma
583
Farrugia, Albert: Safety Issues of Plasma-Derived Products for Treatment of Inherited Bleeding Disorders
589
Tagliaferri, Annarita; Di Perna, Caterina; Biasoli, Chiara; Rivolta, Gianna Franca; Quintavalle, Gabriele; Cervellin, Gianfranco; Barozzi, Marco; Benedettini, Laura; Pattacini, Corrado; for the Haemophilia Centres and Emergency Department Network of the Region of Emilia-Romagna: A Web Site to Improve Management of Patients with Inherited Bleeding Disorders in the Emergency Department: Results at 2 Years

Review Article

550
Batorova, Angelika; Jankovicova, Denisa; Morongova, Anna; Bubanska, Eva; Prigancova, Tatiana; Horakova, Julia; Machyniakova, Marianna; Cervenka, Jan; Chandoga, Jan; Böhmer, Daniel; Mistrik, Martin: Inhibitors in Severe Hemophilia A: 25-Year Experience in Slovakia