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DOI: 10.4103/0970-0358.191324
Antibiotic susceptibility of wound isolates in plastic surgery patients at a tertiary care centre
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Publication History
Publication Date:
13 August 2019 (online)
ABSTRACT
Context: Wound infection increases the hospital stay and adversely affects the recovery of patients. Culture and sensitivity of wound isolates help in proper diagnosis and management of these patients. Aim: To identify common bacteria causing wound infections and their antibiotic sensitivity pattern. Study Design: A cross-sectional study. Place and Duration of Study: Government Medical College and Hospital, Nagpur from October 2013 to October 2015. Materials and Methods: Pus samples were collected by doctors in ward using Sterile Swab Sticks. Bacterial isolates were identified and cultured, and antibiotic culture sensitivity tests were performed. Statistical Analysis Used: Chi-square test. Results: There were a total of 150 patients with infected wounds. Most common organism isolated was Pseudomonas followed by Klebsiella and Staphylococcus aureus. All of these organisms were resistant to most routine antibiotics. Conclusion: We suggest a multidisciplinary approach to wound management, rational drug use, routine microbiological surveillance of wounds and institution of hospital infection control policy.
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Conflicts of interest
There are no conflicts of interest.
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REFERENCES
- 1 Vowden P, Cooper RA. An integrated approach to managing wound infections. European wound management association position document. Management of wound infection. London: Published by MEP; 2006: p. 2-6
- 2 Alexander FM. Wound Infection: Nursing Practice Hospital and Home, the Adult. New York: Churchill Livingstone; 1994
- 3 Dionigi R, Rovera F, Dionigi G, Imperatori A, Ferrari A, Dionigi P. et al. Risk factors in surgery. J Chemother 2001; 13: 6-11
- 4 Sule A, Thanin L, Sule Odu O, Olusonya O. Bacterial pathogens associated with infected wounds in Oguo State University teaching Hospital, Sagon, Nigeria. Afr J Clin Exp Microbiol 2002; 3: 13-6
- 5 Howard JR. Principles of surgery. In: Schwartz SI. editor. Surgical Infections. USA: McGraw Hill Publishers Inc.; 2010: p. 143-75
- 6 Japoni A, Kaloni M, Fenshed SH, Ziyaeyon M, Albuzi A, Mehrabani D. et al. Antibiotic resistant bacteria in hospitalised patients with bloodstream infections; analysis of some associated factors. Iran Red Crescent Med J 2010; 12: 164-72
- 7 Noorbaksh Sabet N, Japoni A, Mehrabain D, Japoni S. Multidrug resistant bacteria in Qoui Hospitals, Central Iron. Iran Red Crescent J 2010; 12: 501-3
- 8 National Committee for Clinical Laboratory Standards. Performance standards for antimicrobial susceptibility testing. 11th ed. Wayne, PA: CLSI; 2001
- 9 Goswami N, Trivedi HR, Goswami AP. Antibiotic sensitivity profile of bacterial pathogens in postoperative wound infections at a tertiary care hospital in Gujrat, India. J Pharm 2011; 2: 158-64
- 10 Ohalete CN, Obi RK, Emeakoroha MC. Bacteriology of different wound infections and their antibiotic susceptibility patterns in Imo state, Nigeria. World J Pharm Sci 2012; 1: 1155-72
- 11 Amoran OE, Sogebi AO, Fatugose OM. Rates and risk factors with SSI in Tertiary care center in South West Nigeria. Int J Trop Dis Health 2013; 3: 25-36
- 12 Pondei K, Fente BG, Oladapo O. Current microbial isolates from wound swabs, their culture and sensitivity pattern at the Niger delta university teaching hospital, Okolobiri, Nigeria. Trop Med Health 2013; 41: 49-53
- 13 Poulsen KB, Wachmann CH, Bremmelgaard A, Sørensen AI, Raahave D, Petersen JV. Survival of patients with surgical wound infection: A case-control study of common surgical interventions. Br J Surg 1995; 82: 208-9
- 14 Sonnerwirth AC, Jarret L. Gradwohls, Clinical Laboratory Methods and Diagnosis 8th ed Vol. 2. Missourri, USA: Mosby Year Book; 1980
- 15 Anvikar AR, Deshmukh AB, Karyakarte R-P, Damle A-S, Patwardhan N-S, Malik A-K. et al. A one year prospective study of 3280 surgical wounds. IJMM 1999; 17: 129-32
- 16 Suchitra JB, Lakshmidei N. Surgical site infections: Assessing risk factors, outcomes and antimicrobial sensitivity patterns. Afr J Microbiol Res 2009; 3: 175-9
- 17 Bibi S, Channa GA, Siddiqui TR, Ahmed W. Pattern of bacterial pathogens in post operative wounds and their sensitivity patterns. J Surg Pak (Int) 2012; 17: 164-7
- 18 Sanjay KR, Prasad MN, Vijay Kumar GS. A study on isolation and detection of drug resistance in gram negative bacilli with special importance to post operative wound infection. J Microbial Antimicrob 2010; 2: 68-75
- 19 Basu S, Ramchuran Panray T, Bali Singh T, Gulati AK, Shukla VK. A prospective, descriptive study to identify the microbiological profile of chronic wounds in outpatients. Ostomy Wound Manage 2009; 55: 14-20
- 20 Bhatt C, Lakhey M. The distribution of pathogens causing wound infections and their antibiotic susceptibility pattern. J Nepal Health Res Counc 2006; 5: 22-6
- 21 Mulu A, Moges F, Tessema B, Kassu A. Pattern and multiple drug resistance of bacterial pathogens isolated from wound infection at University of Gondar Teaching Hospital, Northwest Ethiopia. Ethiop Med J 2006; 44: 125-31
- 22 Manikandan C, Amsath A. Antibiotic susceptibility of bacterial stains isolated from wound infection patients in Pattukkottai, Tamil Nadu, India. Int J Curr Microbiol Appl Sci 2013; 2: 195-203
- 23 Hart CA, Kariuki S. Antimicrobial resistance in developing countries. BMJ 1998; 317: 647-50
Address for correspondence:
-
REFERENCES
- 1 Vowden P, Cooper RA. An integrated approach to managing wound infections. European wound management association position document. Management of wound infection. London: Published by MEP; 2006: p. 2-6
- 2 Alexander FM. Wound Infection: Nursing Practice Hospital and Home, the Adult. New York: Churchill Livingstone; 1994
- 3 Dionigi R, Rovera F, Dionigi G, Imperatori A, Ferrari A, Dionigi P. et al. Risk factors in surgery. J Chemother 2001; 13: 6-11
- 4 Sule A, Thanin L, Sule Odu O, Olusonya O. Bacterial pathogens associated with infected wounds in Oguo State University teaching Hospital, Sagon, Nigeria. Afr J Clin Exp Microbiol 2002; 3: 13-6
- 5 Howard JR. Principles of surgery. In: Schwartz SI. editor. Surgical Infections. USA: McGraw Hill Publishers Inc.; 2010: p. 143-75
- 6 Japoni A, Kaloni M, Fenshed SH, Ziyaeyon M, Albuzi A, Mehrabani D. et al. Antibiotic resistant bacteria in hospitalised patients with bloodstream infections; analysis of some associated factors. Iran Red Crescent Med J 2010; 12: 164-72
- 7 Noorbaksh Sabet N, Japoni A, Mehrabain D, Japoni S. Multidrug resistant bacteria in Qoui Hospitals, Central Iron. Iran Red Crescent J 2010; 12: 501-3
- 8 National Committee for Clinical Laboratory Standards. Performance standards for antimicrobial susceptibility testing. 11th ed. Wayne, PA: CLSI; 2001
- 9 Goswami N, Trivedi HR, Goswami AP. Antibiotic sensitivity profile of bacterial pathogens in postoperative wound infections at a tertiary care hospital in Gujrat, India. J Pharm 2011; 2: 158-64
- 10 Ohalete CN, Obi RK, Emeakoroha MC. Bacteriology of different wound infections and their antibiotic susceptibility patterns in Imo state, Nigeria. World J Pharm Sci 2012; 1: 1155-72
- 11 Amoran OE, Sogebi AO, Fatugose OM. Rates and risk factors with SSI in Tertiary care center in South West Nigeria. Int J Trop Dis Health 2013; 3: 25-36
- 12 Pondei K, Fente BG, Oladapo O. Current microbial isolates from wound swabs, their culture and sensitivity pattern at the Niger delta university teaching hospital, Okolobiri, Nigeria. Trop Med Health 2013; 41: 49-53
- 13 Poulsen KB, Wachmann CH, Bremmelgaard A, Sørensen AI, Raahave D, Petersen JV. Survival of patients with surgical wound infection: A case-control study of common surgical interventions. Br J Surg 1995; 82: 208-9
- 14 Sonnerwirth AC, Jarret L. Gradwohls, Clinical Laboratory Methods and Diagnosis 8th ed Vol. 2. Missourri, USA: Mosby Year Book; 1980
- 15 Anvikar AR, Deshmukh AB, Karyakarte R-P, Damle A-S, Patwardhan N-S, Malik A-K. et al. A one year prospective study of 3280 surgical wounds. IJMM 1999; 17: 129-32
- 16 Suchitra JB, Lakshmidei N. Surgical site infections: Assessing risk factors, outcomes and antimicrobial sensitivity patterns. Afr J Microbiol Res 2009; 3: 175-9
- 17 Bibi S, Channa GA, Siddiqui TR, Ahmed W. Pattern of bacterial pathogens in post operative wounds and their sensitivity patterns. J Surg Pak (Int) 2012; 17: 164-7
- 18 Sanjay KR, Prasad MN, Vijay Kumar GS. A study on isolation and detection of drug resistance in gram negative bacilli with special importance to post operative wound infection. J Microbial Antimicrob 2010; 2: 68-75
- 19 Basu S, Ramchuran Panray T, Bali Singh T, Gulati AK, Shukla VK. A prospective, descriptive study to identify the microbiological profile of chronic wounds in outpatients. Ostomy Wound Manage 2009; 55: 14-20
- 20 Bhatt C, Lakhey M. The distribution of pathogens causing wound infections and their antibiotic susceptibility pattern. J Nepal Health Res Counc 2006; 5: 22-6
- 21 Mulu A, Moges F, Tessema B, Kassu A. Pattern and multiple drug resistance of bacterial pathogens isolated from wound infection at University of Gondar Teaching Hospital, Northwest Ethiopia. Ethiop Med J 2006; 44: 125-31
- 22 Manikandan C, Amsath A. Antibiotic susceptibility of bacterial stains isolated from wound infection patients in Pattukkottai, Tamil Nadu, India. Int J Curr Microbiol Appl Sci 2013; 2: 195-203
- 23 Hart CA, Kariuki S. Antimicrobial resistance in developing countries. BMJ 1998; 317: 647-50