Download PDF
Thromb Haemost 2010; 103(06): 1277-1281
DOI: 10.1160/TH09-10-0711
Letters to the Editor
Schattauer GmbH

Contribution of platelet microparticles generation assay to the diagnosis of type II heparin-induced thrombocytopenia

Francois Mullier   *
1   Hematology Laboratory, UCL Mont-Godinne, Yvoir, Belgium
4   Department of Pharmacy, Drug Design and Discovery Center, FUNDP, University of Namur, Namur, Belgium
,
Nicolas Bailly
1   Hematology Laboratory, UCL Mont-Godinne, Yvoir, Belgium
,
Yvan Cornet
1   Hematology Laboratory, UCL Mont-Godinne, Yvoir, Belgium
,
Eric Dubuc
1   Hematology Laboratory, UCL Mont-Godinne, Yvoir, Belgium
,
Séverine Robert
4   Department of Pharmacy, Drug Design and Discovery Center, FUNDP, University of Namur, Namur, Belgium
,
Jean-Claude Osselaer
2   Blood Transfusion Center, UCL Mont-Godinne, Yvoir, Belgium
,
Christian Chatelain
3   Hematology Department, UCL Mont-Godinne, Yvoir, Belgium
,
Jean-Michel Dogné
4   Department of Pharmacy, Drug Design and Discovery Center, FUNDP, University of Namur, Namur, Belgium
,
Bernard Chatelain
1   Hematology Laboratory, UCL Mont-Godinne, Yvoir, Belgium
› Author Affiliations
Further Information

Publication History

Received: 20 October 2009

Accepted after major revision: 07 February 2010

Publication Date:
22 November 2017 (online)

    Permissions and Reprints

 

* François Mullier is a research fellow of FRIA.


 

  • References

  • 1 Baroletti S, Piovella C, Fanikos J. et al. Heparin-induced thrombocytopenia (HIT): clinical and economic outcomes. Thromb Haemost 2008; 100: 1130-1135.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 2 Chong BH, Isaacs A. Heparin-induced thrombocytopenia: what clinicians need to know. Thromb Haemost 2009; 101: 279-283.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 3 Greinacher A. Heparin-induced thrombocytopenia. J Thromb Haemost 2009; 07 (Suppl. 01) 9-12.
    CrossrefPubMedGoogle Scholar
  • 4 Nowak G. Heparin-induced thrombocytopenia (HIT II) – a drug-associated autoimmune disease. Thromb Haemost 2009; 102: 887-891.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 5 Tardy-Poncet B, Piot M, Chapelle C. et al. Thrombin generation and heparin-induced thrombocytopenia. J Thromb Haemost 2009; 07: 1474-1481.
    CrossrefPubMedGoogle Scholar
  • 6 Hughes M, Hayward CP, Warkentin TE. et al. Morphological analysis of microparticle generation in heparin-induced thrombocytopenia. Blood 2000; 96: 188-194.
    PubMedGoogle Scholar
  • 7 Burnier L, Fontana P, Kwak BR. et al. Cell-derived microparticles in haemostasis and vascular medicine. Thromb Haemost 2009; 101: 439-451.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 8 Dean WL, Lee MJ, Cummins TD. et al. Proteomic and functional characterisation of platelet micro-particle size classes. Thromb Haemost 2009; 102: 711-718.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 9 Morel O, Toti F, Hugel B. et al. Procoagulant micro-particles: disrupting the vascular homeostasis equation?. Arterioscl Thromb Vasc Biol 2006; 26: 2594-2604.
    CrossrefPubMedGoogle Scholar
  • 10 Piccin A, Murphy WG, Smith OP. Circulating microparticles: pathophysiology and clinical implications. Blood Rev 2007; 21: 157-171.
    CrossrefPubMedGoogle Scholar
  • 11 Ueba T, Haze T, Sugiyama M. et al. Level, distribution and correlates of platelet-derived microparticles in healthy individuals with special reference to the metabolic syndrome. Thromb Haemost 2008; 100: 280-285.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 12 Sheridan D, Carter C, Kelton JG. A diagnostic test for heparin-induced thrombocytopenia. Blood 1986; 67: 27-30.
    PubMedGoogle Scholar
  • 13 Whitlatch NL, Perry SL, Ortel TL. Anti-heparin/ platelet factor 4 antibody optical density values and the confirmatory procedure in the diagnosis of heparin-induced thrombocytopenia. Thromb Haemost 2008; 100: 678-684.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 14 Chong BH. Heparin-Induced Thrombocytopenia. In: Platelets. Elsevier Science; 2007. pp. 861-886.
    CrossrefGoogle Scholar
  • 15 Pouplard C, Amiral J, Borg JY. et al. Decision analysis for use of platelet aggregation test, carbon 14-serotonin release assay, and heparin-platelet factor 4 enzyme-linked immunosorbent assay for diagnosis of heparin-induced thrombocytopenia. Am J Clin Pathol 1999; 111: 700-706.
    CrossrefPubMedGoogle Scholar
  • 16 Pouplard C, Amiral J, Borg JY. et al. Differences in specificity of heparin-dependent antibodies developed in heparin-induced thrombocytopenia and consequences on cross-reactivity with danaparoid sodium. Br J Haematol 1997; 99: 273-280.
    CrossrefPubMedGoogle Scholar
  • 17 Robert S, Poncelet P, Lacroix R. et al. Standardization of platelet-derived microparticle counting using calibrated beads and a Cytomics FC500 routine flow cytometer: a first step towards multicenter studies?. J Thromb Haemost 2009; 07: 190-197.
    CrossrefPubMedGoogle Scholar
  • 18 Dachary-Prigent J, Freyssinet JM, Pasquet JM. et al. Annexin V as a probe of aminophospholipid exposure and platelet membrane vesiculation: a flow cytometry study showing a role for free sulfhydryl groups. Blood 1993; 81: 2554-2565.
    PubMedGoogle Scholar
  • 19 Enjeti AK, Lincz LF, Seldon M. Detection and measurement of microparticles: an evolving research tool for vascular biology. Seminars Thromb Haemost 2007; 33: 771-779.
    PubMedGoogle Scholar
  • 20 Krueger LA, Barnard MR, Frelinger AL. 3rd, et al. Immunophenotypic analysis of platelets. Curr Protocols Cytometry. 2002 Chapter 6:Unit 6 10.
    PubMedGoogle Scholar
  • 21 Shah MD, Bergeron AL, Dong JF. et al. Flow cyto-metric measurement of microparticles: pitfalls and protocol modifications. Platelets 2008; 19: 365-372.
    CrossrefPubMedGoogle Scholar
  • 22 Shet AS. Characterizing blood microparticles: technical aspects and challenges. Vasc Health Risk Manag 2008; 04: 769-774.
    CrossrefPubMedGoogle Scholar
  • 23 Lechner D, Weltermann A. Circulating tissue factor-exposing microparticles. Thromb Res 2008; 122 (Suppl. 01) S47-54.
    CrossrefPubMedGoogle Scholar
  • 24 Adcock D. Sample integrity and preanalytical variables. In: Quality in Laboratory Hemostasis and Thrombosis. Wiley-Blackwell; 2009. pp. 31-42.
    CrossrefGoogle Scholar
  • 25 Enjeti AK, Lincz LF, Seldon M. Microparticles in health and disease. Seminars Thromb Haemost 2008; 34: 683-691.
    PubMedGoogle Scholar
  • 26 Dignat-George F, Freyssinet JM, Key NS. Centrifugation is a crucial step impacting microparticle measurement. Platelets 2009; 20: 225-226 author reply 227-228.
    CrossrefPubMedGoogle Scholar
  • 27 Jy W, Horstman LL, Jimenez JJ. et al. Measuring circulating cell-derived microparticles. J Thromb Haemost 2004; 02: 1842-1851.
    CrossrefPubMedGoogle Scholar
  • 28 Foladori P, Quaranta A, Ziglio G. Use of silica microspheres having refractive index similar to bacteria for conversion of flow cytometric forward light scatter into biovolume. Water Res 2008; 42: 3757-3766.
    CrossrefPubMedGoogle Scholar
  • 29 Koch L, Robertson B, Button D. Deduction of the cell volume and mass from the forward scatter intensity of bacteria analyzed by flow cytometry. J Microbiol Methods 1996; 27: 49-61.
    CrossrefPubMedGoogle Scholar