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Thromb Haemost 2007; 97(03): 495-496
DOI: 10.1160/TH06-09-0539
Letters to the Editor
Schattauer GmbH

Association of low protein Z levels with ischemic stroke in young women

Mary J. Heeb
1   Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, California, USA
,
Mark Fisher
2   Departments of Neurology and Anatomy and of Neurobiology, University of California, Irvine, California, USA
,
Annlia Paganini-Hill
3   Department of Preventative Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA
› Author Affiliations
Further Information

Publication History

Received 25 September 2006

Accepted after revision 02 January 2007

Publication Date:
28 November 2017 (online)

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  • References

  • 1 Han X, Fiehler R, Broze Jr GJ. Isolation of a protein Z-dependent plasma protease inhibitor. Proc Natl Acad Sci USA 1998; 95: 9250-9255.
    CrossrefPubMedGoogle Scholar
  • 2 Han X, Fiehler R, Broze Jr GJ. Characterization of the protein Z-dependent protease inhibitor. Blood 2000; 96: 3049-3055.
    PubMedGoogle Scholar
  • 3 Heeb MJ, Cabral KM, Ruan L. Down-regulation of factor IXa in the factor Xase complex by protein Z-dependent protease inhibitor. J Biol Chem 2005; 280: 33819-33825.
    CrossrefPubMedGoogle Scholar
  • 4 Vasse M, Guegan-Massardier E, Borg JY. et al. Frequency of protein Z deficiency in patients with ischemic stroke. Lancet 2001; 357: 933-934.
    CrossrefPubMedGoogle Scholar
  • 5 Heeb MJ, Paganini-Hill A, Griffin JH. et al. Low protein Z levels and risk of ischemic stroke: Differences by diabetic status and gender. Blood Cells Mol Dis 2002; 29: 139-144.
    CrossrefPubMedGoogle Scholar
  • 6 Ayoub N, Esposito G, Barete S. et al. Protein Z deficiency in antiphospholipid-negative Sneddon's syndrome. Stroke 2004; 35: 1329-1332.
    CrossrefPubMedGoogle Scholar
  • 7 Kobelt K, Biasiutti FD, Mattle HP. et al. Protein Z in ischaemic stroke. Br J Haematol 2001; 114: 169-173.
    CrossrefPubMedGoogle Scholar
  • 8 McQuillan AM, Eikelboom JW, Hankey GJ. et al. Protein Z in ischemic stroke and its etiologic subtypes. Stroke 2003; 34: 2415-2419.
    CrossrefPubMedGoogle Scholar
  • 9 Lichy C, Kropp S, Dong-Si T. et al. A common polymorphism of the protein Z gene is associated with protein Z plasma levels and with risk of cerebral ischemia in the young. Stroke 2004; 35: 40-45.
    PubMedGoogle Scholar
  • 10 Lopaciuk S, Bykowska K, Kwiecinski H. et al. Protein Z in young survivors of ischemic stroke. Thromb Haemost 2002; 88: 536
    Article in Thieme ConnectPubMedGoogle Scholar
  • 11 Yin ZF, Huang ZF, Cui J. et al. Prothrombotic phenotype of protein Z deficiency. Proc Natl Acad Sci USA 2000; 97: 6734-6738.
    CrossrefPubMedGoogle Scholar
  • 12 Kemkes-Matthes B, Nees M, Kuhnel G. et al. Protein Z influences the prothrombotic phenotype in factor V Leiden patients. Thromb Res 2002; 106: 183
    CrossrefPubMedGoogle Scholar
  • 13 Martinelli I, Razzari C, Biguzzi E. et al. Low levels of protein Z and the risk of venous thromboembolism. J Thromb Haemost 2005; 3: 2817-2819.
    CrossrefPubMedGoogle Scholar