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Synlett 2008(13): 1949-1952  
DOI: 10.1055/s-2008-1077967
LETTER
© Georg Thieme Verlag Stuttgart ˙ New York

FeCl3/TMSCl: An Effective Catalytic System for the Conjugate Addition of Sodium p-Toluenesulfinate to α,β-Enones

B. Sreedhar*, M. Amarnath Reddy, P. Surendra Reddy
Inorganic and Physical Chemistry Division, Indian Institute of Chemical Technology, Hyderabad 500007, India
Fax: +91(40)27160921; e-Mail: sreedharb@iict.res.in;
Further Information

Publication History

Received 30 January 2008
Publication Date:
15 July 2008 (online)

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Abstract

A new protocol for the β-sulfonation of α,β-unsaturated carbonyl compounds is described. The method employs FeCl3 as catalyst and TMSCl as additive for conjugate addition of sodium p-toluenesulfinate to enones.

Key words

β-sulfonyl ketones - conjugate addition - α,β-unsaturated carbonyl compounds - iron(III) chloride - trimethylsilyl chloride

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