Gastrointestinal bleeding

Introduction

Upper and lower gastrointestinal bleeding remains a potentially serious and frequent challenge, with mortality around 5 % – 10 %. The large number of abstracts devoted to this subject reflects the persistent interest in one of the most important emergencies in gastroenterology and hepatology. This necessarily subjective selection has included the most significant data, but a lot of abstracts listed only in the second part of the reference list are very interesting. Some abstracts that are likely to be included in other DDW Highlights reviews (e. g., capsule endoscopy, endoscopic ultrasound, enteroscopy) have not been described.

References

• 1 Jensen D M, Ohning G V, Singh B. et al . For severe UGI hemorrhage Doppler ultrasound probe is more accurate for risk stratification and helpful for complete endoscopic hemostasis than lesion stigmata alone.  Gastrointest Endosc. 2008;  67 AB81
• 2 Adler A, Papanikolaou I S, Veltzke-Schlieker W. et al . Prospective randomized comparison of a new re-opening endoclip with a standard clipping system.  Gastrointest Endosc. 2008;  67 AB143
• 3 Enestvedt B K, Gralnek I M, Mattek N. et al . Does endoscopic therapy of bleeding peptic ulcers influence need for repeat endoscopy.  Gastrointest Endosc. 2008;  67 AB 82
• 4 Enestvedt B K, Gralnek I M, Mattek N. et al . Adherent clots- to treat or not to treat ?.  Gastrointest Endosc. 2008;  67 AB 255
• 5 Fedorov E D, Yudin O I, Petrov D Y. et al . Argon plasma coagulation vs bipolar electrocoagulation in the endoscopic treatment of bleeding peptic gastroduodenal ulcers. Results of ongoing prospective randomized trial.  Gastrointest Endosc. 2008;  67 AB 256
• 6 Cheung J, Sawisky G, Enns R A. et al . Management of acute peptic ulcer bleeding: a nationwide Canadian survey.  Gastrointest Endosc. 2008;  67 AB291
• 7 Altamirano E, Valdés R, Corral A. et al . Assessment of efficacy, short-term outcome and predictive factors of N-Butyl-2-Cyanoacrylate (Histoacryl) injection for bleeding gastric varices in Hispanic population.  Gastrointest Endosc. 2008;  67 AB249
• 8 Sandhu B S, Mogollon A D, Stravitz R T. et al . A method for endoscopic obturation of gastric varices that maximizes effectiveness without risks of systemic embolization.  Gastrointest Endosc. 2008;  67 AB82
• 9 Kim T A, Lee S M, Park H Y. et al . Role of multi-detector row computed tomography (MDCT) for localization of acute lower gastrointestinal bleeding.  Gastroenterology. 2008;  164 S1280
• 10 Guardiola J, Rodriguez-Moranta F, Berrozpe A. et al . A clinical-endoscopic risk score to predict outcome in acute lower intestinal bleeding.  Gastrointest Endosc. 2008;  67 AB319
• 11 Suda H, Itoh S, Maetani I. Evaluation of the efficiency of urgent colonoscopy to treat bleeding from colorectal diverticulum.  Gastrointest Endosc. 2008;  67 AB321
• 12 Fukunaga S, Saito Y, Matsuda T. et al . Risk factors for delayed bleeding after endoscopic resection for large colorectal tumors.  Gastrointest Endosc. 2008;  67 AB309
• 13 Lee S H, Lee T H, Park J H. et al . Prophylactic APC ablation does not decrease delayed post-polypectomy bleeding.  Gastrointest Endosc. 2008;  67 AB149
• 14 Sedehi D, Soetikno R M, Friedland S. Colonoscopy with polypectomy in anticoagulated patients.  Gastrointest Endosc. 2008;  67 AB282
• 15 Friedland S, Leung C W, Sedehi D. et al . Colonoscopy with polypectomy in patients taking clopidogrel.  Gastrointest Endosc. 2008;  67 AB289
• 16 Gupta R, Sonpal N, Patel N. et al . Prokinetic agent metoclopromide increases the yield of upper endoscopy and decreases the need for second look endoscopy in patients with upper gastrointestinal bleed a randomized prospective study.  Gastrointest Endosc. 2008;  67 AB81-AB82
• 17 Sussman D A, Deshpande A R, Parra J. et al . Intravenous metoclopromide to increase mucosal visualization during endoscopy in patients with acute upper gastrointestinal bleeding: a randomized, controlled study.  Gastrointest Endosc. 2008;  67 AB247
• 18 Bittinger M, Messman H. Endoscopic therapy with a novel multiple clip applicator (ClipMaster 3) in the upper and lower GI-tract.  Gastrointest Endosc. 2008;  67 AB146
• 19 Bretagne J F, Nalet B, Lesur G. et al . Characteristics of GI bleeding occurring in patients on antiplatelet therapy. Results of a prospective cohort of patients recruited in 61 French Hospitals.  Gastroenterology. 2008;  164 W1914
• 20 Nalet B, Bretagne J F, Lesur G. et al . Gastrointestinal bleedings and antiplatelet therapy. A nationwide hospital-based observational survey including 1010 patients.  Gastroenterology. 2008;  164 W1907
• 21 Lau J Y, Sung L J, Metz D C. et al . Systematic review of the epidemiology of complicated peptic ulcer: incidence, recurrence, risk factors and mortality.  Gastroenterology. 2008;  164 A187
• 22 Hershcovici T, Haklai Z, Gordon E S. et al . Acute non variceal upper gastrointestinal bleeding in Israel 1995 – 2004: a significant decrease in incidence, related to a decrease in peptic ulcer bleeding.  Gastroenterology. 2008;  164 W1912
• 23 Nayakama M, Mannen K, Fujimoto K. et al . Low dose aspirin and on demand user of non- steroidal anti-inflammatory drugs are risk factors for bleeding peptic ulcer in Japan.  Gastroenterology. 2008;  164 W1935
• 24 Du Y, Li Z, Diao P. The relationship between H pylori negative peptic ulcer and gastrointestinal bleeding: a prospective multi-center case-control study in China.  Gastroenterology. 2008;  164 W1913
• 25 Cooper G S, Kou T D, Wong R C. Early endoscopy in non variceal upper gi hemorrhage : prevalence and outcome in a population-based sample.  Gastrointest Endosc. 2008;  67 AB88
• 26 Cho H S, Han D S, Byun T J. et al . Comparison of effectiveness of interventional endoscopy in bleeding peptic ulcer according to the timing of endoscopy.  Gastrointest Endosc. 2008;  67 AB247
• 27 Chaparro M, de la Morena F, Barbero A. et al . 3-year retrospective study and 1-year prospective evaluation of a clinical guideline recommending early discharge in selected patients with low-risk non variceal upper gastrointestinal bleeding.  Gastroenterology. 2008;  164 W 1910
• 28 Jensen D M, Kovacs T O, Ohning G V. et al . Hemostasis of very high risk patients with severe non-variceal upper gi hemorrhage comparing injection-hemoclipping with injection-MPEC.  Gastrointest Endosc. 2008;  67 AB106-AB107
• 29 Uyak D. Treatment of acute ulcer bleeding in the upper gastrointestinal tract with fibrin adhesion.  Gastrointest Endosc. 2008;  67 AB78
• 30 Fein F, Koch S, Weber A. et al . Risk factors for rebleeding and death in bleeding ulcers treated with high dose PPI and bipolar coagulation.  Gastroenterology. 2008;  164 W1911
• 31 Khan K H, Kinnear S R, Caddy G. Retrospective observational study of patients admitted with acute upper gi bleed.  Gastrointest Endosc. 2008;  67 AB87
• 32 Taha A S, Angerson W J, Prasad R. et al . Early mortality after upper gastrointestinal bleedings and the use of low-dose aspirin and anti-thrombotic therapy and non-steroidal anti-inflammatory drugs.  Gastroenterology. 2008;  164 W1916
• 33 Loperfido S, Baldo V, Piovesana E. et al . Decline of incidence and mortality of peptic ulcer bleeding between 1983 – 5 and 2002 – 4 : a population-based study in the Triveso area (North-East Italy).  Gastrointest Endosc. 2008;  67 AB88
• 34 Sung J J, Yung M Y, Ma T K. et al . Analysis of cause of death in peptic ulcer bleeding patients: study of a cohort of 10,451 cases.  Gastrointest Endosc. 2008;  67 AB 88
• 35 Buresova M, Keil R, Golanova J. et al . The significance of initial values of blood pressure and heart rate in the evaluation of prognosis in patients with acute bleeding in the upper part of gastrointestinal tract.  Gastrointest Endosc. 2008;  67 AB256
• 36 Samadder N J, Alders G L, Braganza M. et al . Predictors of outcome for patients with gi bleeding attending an urban tertiary hospital.  Gastrointest Endosc. 2008;  67 AB255
• 37 Tamarro L, Di Paolo M C, Zullo A. et al . Timing of urgent endoscopy for upper gastrointestinal bleeding according to clinical criteria : a prospective study.  Gastrointest Endosc. 2008;  67 AB243
• 38 Toki M, Yamaguchi Y, Nakamura K. et al . Predictive risk factors for rebleeding and thirty-day mortality after endoscopic hemostasis in elderly bleeding peptic ulcers patients.  Gastrointest Endosc. 2008;  67 AB240
• 39 Pang S H, Ching J, Lau J Y. et al . A validation and comparison of the Blatchford, pre-endoscopic Baylor and clinical Rockall scoring systems in predicting the need for therapeutic endoscopy in patients with upper gastrointestinal haemorrhage.  Gastrointest Endosc. 2008;  67 AB 256
• 40 Saperas E, Videla S, Bayarri C. et al . Applicability of the Rockall scoring system and prediction of rebleeding and mortality after combined pharmacologic and endoscopic treatment of high-risk bleeding peptic ulcers.  Gastrointest Endosc. 2008;  67 AB 255
• 41 Papamatheakis D G, Patel M D, Singal B. et al . Rockall risk stratification of non-variceal upper gi bleed in a community teaching hospital and is accuracy in the setting of pro-hemorrhagic medications.  Gastrointest Endosc. 2008;  67 AB 255
• 42 Pang S H, Ching J, Lau J Y. et al . A validation and comparison of the Blatchford, pre-endoscopic Baylor and clinical Rockall scoring systems in predicting the need for therapeutic endoscopy in patients with upper gastrointestinal haemorrhage.  Gastrointest Endosc. 2008;  67 AB256-AB257
• 43 Basavaraju U, Thomson J M, Armour D L. et al . Influence of aspirin and non-steroidal anti-inflammatory drugs use on the outcomes of bleeding peptic ulcers: 10 year experience of a specialized bleeding unit.  Gastroenterology. 2008;  164 W1902
• 44 Young S D, Elmunzer J E, Laine L. et al . Systematic review of the predictors of recurrent hemorrhage after endoscopic hemostasis therapy for bleeding peptic ulcers.  Gastroenterology. 2008;  164 W1905
• 45 Poh C H, Fock K M, Teo E. et al . Effect of intravenous infusion versus intravenous bolus omeprazole in patients with bleeding peptic ulcer.  Gastroenterology. 2008;  164 W1909
• 46 Lee Y S, Kim I S, Kim W. et al . No addictive effect of somatostatin to proton pump inhibitor in patients with peptic bleeding ulcer.  Gastroenterology. 2008;  164 W1908
• 47 Shah A, Bemanian S, Laine L. Prospective randomized comparison of the effect of oral PPI vs Intravenous bolus + constant infusion PPI on intragastric pH in patients with bleeding ulcers: is intermittent oral PPI therapy sufficient?.  Gastroenterology. 2008;  164 184
• 48 Barkun A, Adam V. The cost-effectiveness of high-dose intravenous proton pump inhibition administered after endoscopic hemostasis using quality-adjusted life years as unit of effectiveness.  Gastrointest Endosc. 2008;  67 AB236
• 49 Kim H K, Kim J S, Cho Y S. et al . Effect of high dose oral rabeprazole on recurrent bleeding after endoscopic treatment of bleeding peptic ulcers: a preliminary report.  Gastrointest Endosc. 2008;  67 AB257
• 50 Pham C Q, Barkun A, Bardou M. et al . Proton pump inhibitors versus histamine 2 receptor antagonists or sucrafate for stress related mucosal bleeding prophylaxis in critically Ill patients: a follow-up meta-analysis.  Gastroenterology. 2008;  164 W1904
• 51 Hirayama Y, Hoteya S, Kikuchi . et al . Risk factors of delayed bleeding after endoscopic submucosal dissection from gastric tumors.  Gastrointest Endosc. 2008;  67 AB284
• 52 Yamamoto T, Ishii T, Hattori K. et al . Possible role of gastroprotective agents on preventing gastroduodenal mucosal injury in patients taking low-dose aspirin.  Gastrointest Endosc. 2008;  67 AB276-AB277
• 53 Velayos B, Fernandez L, Almaraz A. et al . Validation in the usual practice of a simultaneous urea breath test during the urgent gastroscopy in the peptic bleeding.  Gastrointest Endosc. 2008;  67 AB275-AB276
• 54 Lara L F, Sreenarasimhaiah J, Tang S J. et al . Localization, efficacy of therapy and outcomes of Dieulafoy lesions of the GI tract - The UT Southwestern GI bleed team experience.  Gastrointest Endosc. 2008;  67 AB433
• 55 Li C Z. Modified sandwich method in endoscopic cyanoacrylate injection: an attempt to decrease ectopic embolism.  Gastrointest Endosc. 2008;  67 AB244
• 56 Kato T, Araki H, Sugiyama A. et al . Gastric antral vascular ectasia (GAVE): how to prevent bleeding-induced anemia in patients with portal hypertension?.  Gastrointest Endosc. 2008;  67 AB257
• 57 Araki H, Kimura Y, Yasuda Y. et al . Efficacy of endoscopic variceal ligation for esophageal varices in patients with hepatocellular carcinoma, comparison with patients without hepatocellular carcinoma.  Gastrointest Endosc. 2008;  67 AB247
• 58 Yuki M, Kazumori H, Takuwa S. et al . Long-term results of endoscopic injection sclerotherapy for esophageal varices in adults: 20-year prospective evaluation.  Gastrointest Endosc. 2008;  67 AB190
• 59 Luz G O, Maluf-Filho F, Matuguma S E. et al . Comparison of endoscopic sclerosis with endoscopic band ligation for hemostasis of active haemorrhage elicited by rupture of esophageal varices.  Gastrointest Endosc. 2008;  67 AB189
• 60 Nagamine N. Strategy for prophylactic patients with risk risky esophageal varices complicated with hepatocellular carcinoma.  Gastrointest Endosc. 2008;  67 AB193-AB194
• 61 Tafarel J, Lenz L, Martins F P. et al . Predicting the presence of esophageal varices in cirrhotic patients using MELD, APRI, Child-Pugh score, platelets and liver function tests.  Gastrointest Endosc. 2008;  67 AB287
• 62 Pilette C, Bour B, Lesgourges B. et al . Lower gastrointestinal bleeding in the general population: preliminary results of a french prospective study including more than 1000 patients.  Gastroenterology. 2008;  164 T1039
• 63 Johannes R S, Tabak Y P, Sun X. et al . Development and validation of a simple risk classification rule for patients with acute lower gastrointestinal bleeding.  Gastrointest Endosc. 2008;  67 AB83
• 64 McKay R, McNamara D. The role of flexible sigmoidoscopy in acute lower GI bleeding.  Gastrointest Endosc. 2008;  67 AB 321
• 65 Okazaki H, Fujiwara Y, Sugimori S. et al . Prevalence of small bowel bleeding in patients with gastrointestinal overt bleeding: a mutli-center experience of 1052 consecutive patients.  Gastrointest Endosc. 2008;  67 AB263
• 66 Staples J, Mcloughlin M, Lakzadeh P. et al . Prospective evaluation of patients referred for obscure bleeding: how many patients actually have small bowel bleeding? Update at one year.  Gastrointest Endosc. 2008;  67 AB258
• 67 Berrozpe A, Rodriguez-Moranta F, Guardiola J. et al . External validation of the strate’s predictive model of severity in lower intestinal bleeding.  Gastrointest Endosc. 2008;  67 AB320
• 68 Chen J, Shergill A K, McQuaid K R. et al . Endoscopic evaluation and management of colonic postpolypectomy hemorrhage.  Gastrointest Endosc. 2008;  67 AB320
• 69 Karamanolis G, Kalli T, Misailidis N. et al . Is argon plasma coagulation the optimal treatment for rectal bleeding after radiotherapy?.  Gastrointest Endosc. 2008;  67 AB320
• 70 Somnay K, Gutkin E, Khillan R. et al . Argon plasma coagulation with 1 % alum irrigation reduces rebleeding associated with radiation proctitis.  Gastrointest Endosc. 2008;  67 AB139
• 71 Gonzalez M L, Cariello M, Macías G ómez. et al . Argon plasma coagulation for the treatment of radiation induced proctitis.  Gastrointest Endosc. 2008;  67 AB320
• 72 Cukor B, Cryer B L. The risk of rebleeding after an index GI bleed in patients on anticoagulation.  Gastrointest Endosc. 2008;  67 AB243
• 73 Gerson L B, Ullah N. Health-related quality of life in patients with chronic gastrointestinal hemorrhage.  Gastrointest Endosc. 2008;  67 AB267
• 74 Giday S A, Wroblewski R J, Magno P. et al . Novel endoscopic techniques are effective for control of hemorrhage during NOTES.  Gastrointest Endosc. 2008;  67 AB113-AB114
• 75 Sedlack R E. Assessing the impact of stimulation training on endoscopic hemostasis skills.  Gastrointest Endosc. 2008;  67 AB296
• 76 Jensen D M, Machicado G A, Singh B. et al . Depth of hemoclipping, gross injury, histologic inflammation and fibrosis with different hemoclips or MPEC in a randomized hemostasis study of chronic canine ulcers.  Gastrointest Endosc. 2008;  67 AB254
• 77 Jensen D M, Machicado G A, Singh B. et al . Depth of hemoclip attachment, tissue injury and fibrosis after hemostasis of bleeding acute canine ulcers in a randomized controlled study.  Gastrointest Endosc. 2008;  67 AB256
• 78 Maiss J, Ende A, Heide R. et al . Hemodynamic efficacy of sequential endoscopic clip application using the new Olympus HX-110/60 reloable clipping device in the treatment of spurting bleedings.  Gastrointest Endosc. 2008;  67 AB294
• 79 Pollack M J, Elmunzer J E, Trunzo J A. et al . Initial evaluation of a novel prototype forward-viewing echoendoscope in a porcine arterial bleeding model.  Gastrointest Endosc. 2008;  67 AB81
• 80 Vattasseril R, Eldarawy W, Sharma D. et al . Fecal occult blood test, not anemia, may predict increased risk for gastrointestinal bleeding in patients treated for acute myocardial infarction.  Gastroenterology. 2008;  164 T1046
• 81 Lee W S, Cho S B, Park C H. et al . A prospective, randomized trial of sucralfate versus proton pump inhibitor on prevention of hemorrhage from the artificial ulcer after endoscopic submucosal dissection.  Gastrointest Endosc. 2008;  67 AB281