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Planta Med 2008; 74(2): 171-174
DOI: 10.1055/s-2008-1034278
Natural Product Chemistry
Original Paper
© Georg Thieme Verlag KG Stuttgart · New York

Cytotoxic Activities of Flavonoid Glycoside Acetates from Consolida oliveriana

Jesús G. Díaz1 , Armando J. Carmona1 , Fernando Torres2 , José Quintana2 , Francisco Estévez2 , Werner Herz3
  • 1Instituto Universitario de Bio-Orgánica ”Antonio González”, La Laguna, Tenerife, Spain
  • 2Departamento de Bioquímica, Biología Molecular y Fisiologia, Centro de Ciencias de la Salud, Universidad de las Palmas de Gran Canaria, Gran Canaria, Spain
  • 3Department of Chemistry and Biochemistry, The Florida State University, Tallahassee, Florida, USA
Further Information

Publication History

Received: October 8, 2007 Revised: November 7, 2007

Accepted: December 3, 2007

Publication Date:
23 January 2008 (online)

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Abstract

The flavonoids kaempferol, quercetin, trifolin, hyperoside 2″- and 6″- acetates, 7-glucotrifolin, biorobin and robinin were isolated from the aerial parts of Consolida oliveriana. Their derivatives kaempferol tetraacetate, quercetin pentaacetate, trifolin heptaacetate and hyperoside octaacetate exhibited significant cytotoxicity in vitro against three human cell lines HL-60, U937 and SK-MEL-1 while hyperoside 2″-acetate, hyperoside-6″-acetate, glucotrifolin decaacetate and heptamethyltrifolin were inactive.

Key words

Consolida oliveriana - Ranunculaceae - flavonoids - flavonoid acetates - cytoxicity

References

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Professor Werner Herz

Department of Chemistry and Biochemistry

The Florida State University

Tallahassee

Florida 32306-4390

USA

Phone: +1-850-644-2774

Fax: +1-850-644-8281

Email: jdulin@chem.fsu.edu

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