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Synthesis 2008(7): 1065-1068  
DOI: 10.1055/s-2008-1032128
PAPER
© Georg Thieme Verlag Stuttgart · New York

A Novel Three-Component Reaction Involving Quinoline, Dimethyl Acetylene­dicarboxylate, and C-H Acids Leading to the Synthesis of Pyrroloquinoline­ Derivatives

Vijay Nair*a, Satheesh Devipriyaa, Eringathodi Sureshb
a Organic Chemistry Section, National Institute for Interdisciplinary Science and Technology (Formerly Regional Research Laboratory), CSIR, Trivandrum 695 019, India
Fax: +91(471)2491712; e-Mail: vijaynair_2001@yahoo.com;
b Analytical Science Discipline, Central Salt and Marine Chemicals Research Institute, Bhavnagar 364 002, India
Further Information

Publication History

Received 2 February 2007
Publication Date:
06 March 2008 (online)

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Abstract

The zwitterion derived from quinoline and dimethyl acetylenedicarboxylate on reaction with C-H acids afforded pyrroloquinoline derivatives.

Key words

zwitterion - quinoline - pyrroloquinoline - Michael addition

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10

Single crystal X-ray data for 4 has been deposited at the Cambridge Crystallographic Data Centre and allocated the deposition number CCDC 627201.