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DOI: 10.1055/s-2008-1027131
© Georg Thieme Verlag KG Stuttgart · New York
Antiangiogene Therapie am Auge - bewährte und neue Therapieansätze
Anti-Angiogenic Therapy in Ocular Disease - Current and Future StrategiesPublication History
Eingegangen: 30.11.2007
Angenommen: 7.1.2008
Publication Date:
31 January 2008 (online)
![](https://www.thieme-connect.de/media/klimo/200801/lookinside/thumbnails/10.1055-s-2008-1027131-1.jpg)
Zusammenfassung
Aus der Onkologie kommend hat die antiangiogene Therapie die Augenheilkunde in den letzten Jahren verändert. Sie eröffnet neue Optionen für die Behandlung der altersabhängigen Makuladegeneration, des diabetischen Makulaödems, nach Venenverschlüssen und möglicherweise auch von Erkrankungen der Hornhaut mit starker Blut- und Gefäßneubildung. In dieser Arbeit soll ein Überblick über neue medikamentöse therapeutische Strategien gegeben werden, die sich derzeit in der klinischen Erprobung oder Anwendung befinden.
Abstract
Originating from therapeutic concepts in oncology, angioinhibitory strategies have changed the way ophthalmological patients are treated for a variety of diseases like age-related macular degeneration, diabetic retinopathy or retinal vein occlusion. It is likely that these therapeutic options will not be limited to retinal disease, but will also prove useful for corneal disorders associated with lymph- or angiogenesis. This review is intended to provide a concise overview of the current options investigated in clinical trials.
Schlüsselwörter
Pharmakologie - Retina - Kornea
Key words
retina - pharmacology - cornea
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PD Hansjürgen Agostini
Augenklinik, Uniklinik Freiburg
Killianstr.5
79106 Freiburg
Phone: ++ 49/7 61/2 70 40 46
Fax: ++ 49/7 61/2 70 41 74
Email: hansjuergen.agostini@uniklinik-freiburg.de