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Am J Perinatol 1997; 14(8): 469-473
DOI: 10.1055/s-2007-994182
ORIGINAL ARTICLE

© 1997 by Thieme Medical Publishers, Inc.

Echovirus Type 22 Outbreak Associated with Gastro-Intestinal Disease in a Neonatal Intensive Care Unit

Emanuel Birenbaum1 , Rachel Handsher2 , Jacob Kuint1 , Ron Dagan3 , Brian Raichman1 , Ella Mendelson2 , Nehama Linder1
  • 1Department of Neonatalogy, Chaim Sheba Medical Center, Tel-Hashomer and the Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel
  • 2The Central Virology Laboratory, Chaim Sheba Medical Center, Tel-Hashomer, Tel-Hashomer, Israel
  • 3Pediatric Infectious Disease Unit, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel
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Publication Date:
04 March 2008 (online)

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ABSTRACT

An echovirus type 22 outbreak involving 19 neonatal intensive care unit (NICU) patients during the months of October and November 1992 is reported. Twelve infants presented with diarrhea, 7 of whom had bloody stools and x-ray findings compatible with early stages of necrotizing enterocolitis, while one infant demonstrated characteristic pneumatosis intestinalis. Outbreaks of echovirus type 22 infection in premature infants have rarely been reported. The possibility of Echovirus 22 infection should be considered in neonatal gastrointestinal disease associated with features of necrotizing enterocolitis.

Keywords

Echovirus 22 - outbreak - neonatal - ICU