Subscribe to RSS
DOI: 10.1055/s-2007-993200
© Georg Thieme Verlag KG Stuttgart · New York
Metastatic Brain Tumor Surgery Using Fluorescein Sodium: Technical Note
Publication History
Publication Date:
22 January 2008 (online)
Abstract
As for the surgical treatment of glioma, the recent employment of fluorescence-guided resection using 5-aminolevulinic acid (5-ALA) or high-dose fluorescein sodium has increased the rate of radical tumor resection. On the other hand, there is no specific technique for metastatic brain tumor surgery. We have used a fluorescence-guided tumor resection procedure with the aid of high-dose fluorescein sodium in surgery for metastatic brain tumor. Fluorescein sodium has been used in 13 cases, and achieved effective stainability in all cases. Fluorescein sodium is inexpensive, highly safe, and comparatively easy to use, and does not require any special equipment. We believe that the use of fluorescein sodium is beneficial for resection of the metastatic brain tumor.
Key words
metastatic brain tumor - surgical treatment - fluorescein sodium
References
- 1 Stummer W, Pichlmeier U, Meinel T, Wiestler OD, Zanella F, Reulen HJ. for the ALA-Glioma Study Group . Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: randomized controlled multicentre phases I trial. Lancet Oncol. 2006; 7 392-401
- 2 Moore GE, Peyton WT, French LA, Walker WW. The clinical use of fluorescein in neurosurgery. J Neurosurg. 1948; 5 392-398
- 3 Murray KJ. Improved surgical resection of human brain tumors: Part. A preliminary study. Surg Neurol. 1982; 17 316-319
- 4 Shinoda J, Yano H, Yoshimura S, Okumura A, Kaku Y, Iwama T, Sakai N. Fluorescence-guided resection of glioblastoma multiforme by using high-dose fluorescein sodium. J Neurosurg. 2003; 99 597-603
Correspondence
T. OkudaMD
Department of Neurosurgery
Kinki University School of Medicine
377-2 Ohno-Higashi Osaka-Sayama
Osaka 589-8511
Japan
Phone: +81/723/66 02 21 (ext 3547)
Fax: +81/723/65 69 75
Email: okuda@neuro-s.med.kindai.ac.jp