J Reconstr Microsurg 2007; 23(7): 391-398
DOI: 10.1055/s-2007-992347
© Thieme Medical Publishers

New Pure Motor Nerve Experimental Model for the Comparative Study between End-to-End and End-to-Side Neurorrhaphy in Free Muscle Flap Neurotization

Georgia-Alexandra Ch Spyropoulou1 , Efstathios G. Lykoudis2 , Anna Batistatou3 , Apostolos E. Papalois4 , George Tagaris5 , Emmanouil Pikoulis6 , Elias Bastounis6 , Othon Papadopoulos1
  • 1Department of Plastic Surgery, “A. Siggros” University Hospital, Athens, Greece
  • 2Department of Plastic Surgery and Burns, “A. Siggros” University Hospital, Athens, Greece
  • 3Department of Pathology, Ioannina University Hospital, Ioannina, Greece
  • 4Experimental Research Center-ELPEN, Athens, Greece
  • 5Department of Neurology, “G. Gennimatas” General Hospital, Athens, Greece
  • 6First Surgical Clinic, University of Athens, “Laikon” General Hospital, Athens, Greece
Further Information

Publication History

Publication Date:
31 October 2007 (online)

ABSTRACT

The present study demonstrates a new experimental model to compare the efficacy of end-to-end and end-to-end neurorrhaphy in free muscle flap neurotization. Forty animals were used, divided into four equal groups named A, B, C and D. The peripheral stump of the thoracodorsal nerve was stitched end-to-end in groups A and C and end-to-side in groups B and D to the long thoracic nerve. Free functional muscle transfer was simulated by putting vascular clamps to the thoracodorsal artery (FD SS8R, F: 15 to 20 g) and vein (FD SS6R, F: 10 to 15 g) for 60 minutes and transecting and then restitching the origin and insertion of the latissimus dorsi muscle. Electromyographic and histological studies were performed 150 days following completion of the experiment. The results could indicate the possibility that end-to-side neurorrhaphy might be used in free functional muscle transfer as an alternative to end-to-end neurorrhaphy. We believe that the proposed experimental model is useful for the comparative study between end-to-end and end-to-side neurorrhaphy in free muscle flap neurotization, as these are pure motor nerves and innervate synergistic muscles, are in close approximation, and have similar diameters.

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0 Presented at the World Congress for Reconstructive Microsurgery, Athens, 24-26 June 2007

Dr. Georgia-Alexandra Ch SpyropoulouM.D. Ph.D. 

63 Dimitrakopoulou str

Athens 16673, Greece