J Reconstr Microsurg 1984; 1(1): 11-19
DOI: 10.1055/s-2007-1007048
ORIGINAL ARTICLE

© 1984 by Thieme Medical Publishers, Inc.

Revascularized Segmental Diaphyseal Bone Transfers in the Canine

An Analysis of ViabilityMichael A. Arata, Michael B. Wood, William P. Cooney III 
  • Mayo Clinic and Mayo Foundation, Rochester, Minnesota
Further Information

Publication History

Publication Date:
08 March 2008 (online)

ABSTRACT

The biologic behavior of free revascularized bone segments was investigated using a unique canine model. Conventional methods to assess bone kinetics included the histologic osteocyte count, tetracycline uptake, appositional bone formation rate, and quantitative microradiography. The percentage of viable osteocytes in the revascularized segment was 52.4%, compared with 66.8% in the normal controls and 28.5% in the nonrevascularized segment. These differences were statistically significant. Both qualitative and quantitative differences were noted regarding deposition of tetracycline. On the basis of this study, we conclude that an apparently successful vascularized bone transfer retains a degree of viability greater than a conventional bone graft but less than that of normal undisturbed bone.