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Synthesis 2005(3): 374-380  
DOI: 10.1055/s-2004-834938
PAPER
© Georg Thieme Verlag Stuttgart · New York

Preparation of Nitrogen-Containing 25-Membered Pentaolefinic Macrocycles: (E,E,E,E,E)-1,6,11,16,21-Penta(arylsulfonyl)-1,6,11,16,21-pentaazacyclopentacosa-3,8,13,18,23-pentaenes

Belén Blancoa, Jesper Christensena, Ignasi Maurela, Roser Pleixats*a, Anna Serraa, Anna Pla-Quintanab, Anna Roglans*b, Jordi Benet-Buchholzc
a Department of Chemistry, Universitat Autònoma de Barcelona, Cerdanyola, 08193 Barcelona, Spain
Fax: +34(9)35811265, +34(9)72418150; e-Mail: roser.pleixats@uab.es and anna.roglans@udg.es;
b Department of Chemistry, Universitat de Girona, Campus de Montilivi, 17071 Girona, Spain
c Bayer Industry Services, Analytics X-ray Laboratory, Geb. Q18, Raum 490, Bayer AG, 51368 Leverkusen, Germany
Further Information

Publication History

Received 26 July 2004
Publication Date:
01 December 2004 (online)

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Abstract

A stepwise preparation of a series of nitrogen-containing 25-membered pentaolefinic macrocycles is presented. The corresponding arenesulfonamides and trans-1,4-dibromo-2-butene served as precursors for the synthesis.

Key words

alkenes - heterocycles - macrocycles - sulfonamides

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8

Crystallographic data (excluding structure factors) for the structure in this paper has been deposited with the Cambridge Crystallographic Data Centre as supplementary publication number CCDC 230218. Copies of the data can be obtained, free of charge, on application to CCDC, 12 Union Road, Cambridge, CB2 1EZ, UK [fax: +44 (1223)336033 or e-mail: deposit@ccdc.cam.ac.uk].